Results 101 to 110 of about 976,226 (308)

Influence of L-sorbose on the location of β-glucosidase in Trichoderma pseudokoningii [PDF]

open access: yesFEMS Microbiology Letters, 1983
The effect of l-sorbose on growth, morphology, cell wall composition and β-glucosidase location has been examined with Trichoderma pseudokoningii. Sorbose-grown cultures exhibited a longer lag phase, a tendency to more frequent hyphal branching and showed a decreased cell wall content of β-1,3-glucan.
openaire   +1 more source

Molecular dynamics simulations reveal the inhibitory mechanism of Withanolide A against α-glucosidase and α-amylase

open access: yes, 2023
Diabetes mellitus (DM) is a global chronic disease characterized by hyperglycemia and insulin resistance. The unsavory severe gastrointestinal side-effects of synthetic drugs to regulate hyperglycemia have warranted the search for alternative treatments ...
Mohd Hayrie, Mohd Hatta   +5 more
core   +1 more source

From Prediction to Decision Making: PBPK and QSP as Regulatory‐Grade NAMs

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
New approach methodologies (NAMs) encompass a diverse and rapidly evolving set of experimental and computational tools designed to generate human‐relevant mechanistic data for use in drug development and regulatory decision making. Experimental NAMs provide insights into drug disposition, pharmacological activity, and disease biology that are difficult
Karen Rowland Yeo, Piet H. van der Graaf
wiley   +1 more source

α‑Glucosidase and PTP-1B Inhibitors from Malbranchea dendritica

open access: yesACS Omega, 2021
Daniela Rebollar-Ramos   +6 more
doaj   +1 more source

MOESM1 of A novel β-glucosidase from Saccharophagus degradans 2-40T for the efficient hydrolysis of laminarin from brown macroalgae

open access: yes, 2018
Additional file 1: Table S1. Kinetic parametersa of Bgl1B in the hydrolysis of different types of substrates.
Kim, Dong   +3 more
openaire   +1 more source

Kinetics of Hypoglycemic α-Glucosidase Inhibitory Protein

open access: yes, 2018
The activity of a-glucosidase enzyme (EC 3.2.1.20) was inhibited by 40.3% by an extracellular inhibitory protein which isolated from the culture filtrate of Aspergillus brasiliensis ATCC-16404. The maximum activity of this protein and fungal mycelial dry
Fahad A. Al-Dhabaan, Fahad Al-Dhabaan
core   +1 more source

Visible‐Light‐Mediated Synthesis of Biscoumarins Utilizing Photocaged Sulfonic Acid as the Catalyst

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
A mild visible light approach for the synthesis of biscoumarins utilizing arylazo sulfones as the photoacid generator under 467 nm irradiation is introduced. Throughout the years, biscoumarin derivatives, known for their diverse biological properties, have attracted extensive synthetic interest.
Athina S. J. Shkembi   +5 more
wiley   +1 more source

Inhibitory Mechanism of Aloe Emodin on α-Glucosidase and Synergistic Effect with Acarbose [PDF]

open access: yesShipin Kexue
In order to investigate the interaction between aloe emodin and α-glucosidase, enzyme kinetics, ultraviolet (UV) spectroscopy, infrared (IR) spectroscopy and fluorescence spectroscopy were employed to investigate the inhibitory mechanism of aloe emodin ...
QIN Chaofeng, LI Jiao, HAO Jingwen, BU Yaqin, LI Sheng, CHEN Naidong
doaj   +1 more source

β-Glucosidases in the yeastPichia polymorpha [PDF]

open access: yesFEMS Microbiology Letters, 1979
T.G. Villa, V. Notario, J.R. Villanueva
openaire   +1 more source

MOESM4 of A novel β-glucosidase from Saccharophagus degradans 2-40T for the efficient hydrolysis of laminarin from brown macroalgae

open access: yes, 2018
Additional file 4: Table S2. Comparison of optimum conditions and substrate specificities of various characterized β-glucosidases (EC 3.2.1.21) in GH1.
Kim, Dong   +3 more
openaire   +1 more source

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