Results 321 to 330 of about 1,799,019 (357)

Performance of β-Glucosidase produced by Ganoderma lucidum using Waste Substrate as Carbon Source

Journal of Biochemistry, Microbiology and Biotechnology, 2013
Oil palm empty fruit bunch (OPEFB) was used for the production of β-glucosidase by Ganoderma lucidum in submerged fermentation. The activity of β-glucosidase had shown an improvement by going from pH 4 to 6 and declined towards alkaline pH. The highest activity (47.75 U/mL) was obtained at pH 6 with 2.0 mm size of substrate’s particle.
Nur Haziqah Aniyah Salihan, Arbakariya Ariff, Mohd Rafein Zakaria, Suraini Abd-Aziz, Md Noor Bd Wahab, Helmi Wasoh   +5 more
openaire   +1 more source

In vitro and in vivo inhibitory effect of anthocyanin-rich bilberry extract on α-glucosidase and α-amylase

, 2021
The inhibition of glycosidase activity is regarded as an effective treatment for diabetes mellitus. Bilberry (Vaccinium myrtillus L.) fruit has a high content of anthocyanins with various biological activities.
Yanglin Ji, Dong Liu, Yan Jin, Juan Zhao, Jiang Zhao, Heyu Li, Liwei Li, Huan Zhang, Hao Wang   +8 more
semanticscholar   +1 more source

Metabolite profiling, antioxidant and α-glucosidase inhibitory activities of buckwheat processed by solid-state fermentation with Eurotium cristatum YL-1.

Food Research International, 2021
Buckwheat was processed by solid-state fermentation (SSF) with the probiotic fungal strain Eurotium cristatum YL-1. The effects of SSF on the phytochemical content, as well as the antioxidant and α-glucosidase inhibitory activities, on buckwheat were ...
Yu Xiao, Xing Wu, Xin-Tong Yao, Yulian Chen, Chi-Tang Ho, Cheng-hui He, Zongjun Li, Yuanliang Wang   +7 more
semanticscholar   +1 more source

Exploring synergistic inhibitory mechanisms of flavonoid mixtures on α-glucosidase by experimental analysis and molecular dynamics simulation.

Food Chemistry
The study was the first to evaluate the synergistic interaction of luteolin + quercetin, luteolin + 3-O-methylquercetin, and quercetin + 3-O-methylquercetin mixtures on α-glucosidase and the binding mechanisms were explored using both experimental and ...
Junkun Pan, Muhammad Nawaz, Jiechao Liu, Hui Liu, Zhenzhen Lv, Wenbo Yang, Zhonggao Jiao, Qiang Zhang   +7 more
semanticscholar   +1 more source

Extraction, identification, and molecular mechanisms of α-glucosidase inhibitory peptides from defatted Antarctic krill (Euphausia superba) powder hydrolysates.

International Journal of Biological Macromolecules
The objective of this study was to explore the potential of Antarctic krill-derived peptides as α-glucosidase inhibitors for the treatment of type 2 diabetes.
Kewei Zheng, Yuanyuan Wu, Qingfei Dai, Xiaojun Yan, Yu Liu, Di Sun, Zhongjie Yu, Shuoqi Jiang, Qingbao Ma, Wei Jiang   +9 more
semanticscholar   +1 more source

The antioxidant activities, inhibitory effects, kinetics, and mechanisms of artocarpin and α-mangostin on α-glucosidase and α-amylase.

International Journal of Biological Macromolecules, 2022
This study investigated the antioxidant activities, inhibitory activities and the interaction mechanisms of artocarpin and α-mangostin on α-amylase and α-glucosidase.
Qirou Wang, Ruilin Li, Nannan Li, Yanan Jia, Yajie Wang, Yue Chen, P. Panichayupakaranant, Haixia Chen   +7 more
semanticscholar   +1 more source

Inhibition mechanism of ferulic acid against α-amylase and α-glucosidase.

Food Chemistry, 2020
The inhibitory mechanisms of ferulic acid against α-amylase and α-glucosidase were investigated by enzyme kinetic analysis, circular dichroism (CD), Fourier-transform infrared (FT-IR) spectroscopy, fluorescence quenching and molecular docking.
Yuxue Zheng, Jinhu Tian, Wenhan Yang, Shiguo Chen, Donghong Liu, Haitian Fang, Huiling Zhang, Xingqian Ye   +7 more
semanticscholar   +1 more source

Chromone-based benzohydrazide derivatives as potential α-glucosidase inhibitor: Synthesis, biological evaluation and molecular docking study.

Bioorganic chemistry (Print), 2022
In order to find new α-glucosidase inhibitors with high efficiency and low toxicity, novel chromone-based benzohydrazide derivatives 6a-6s were synthesized and characterized through 1H NMR, 13C NMR, and HRMS. All the new synthesized compounds were tested
Meiyan Fan, Wei-Qiang Yang, Zhiyun Peng, Yan He, Guangcheng Wang   +4 more
semanticscholar   +1 more source

POTENTIAL INHIBITORS OF α-GLUCOSIDASE AND α-AMYLASE ENZYMES FROM LOCALLY AVAIALABLE FRUIT WASTES BY SOLID STATE FERMENTATION

Chemical and Natural Resources Engineering Journal (Formally known as Biological and Natural Resources Engineering Journal), 2019
ABSTRACT: A   therapeutic   approach   for   treating   diabetes   is   to   decrease   the   post-prandial hyperglycaemia. This is done by retarding the absorption of glucose through the inhibition of the carbohydrate hydrolyzing enzymes, α-amylase and α-glucosidase, in the digestive tract.
ANUMSIMA AHMAD BARKAT, Parveen Jamal, AZLIN SUHAIDA AZMI, IBRAHIM ALI NOORBACHA, DACHYAR ARBAIN, ZULKARNAIN MOHAMED IDRIS   +5 more
openaire   +1 more source

Solvent Effect on Phenolic Compounds Extraction, Antioxidant Capacities and Α-Amylase and Α-Glucosidase Inhibition of Clematis flammula and Periploca angustifolia

Journal of Pharmaceutics & Drug Delivery Research, 2016
Solvent Effect on Phenolic Compounds Extraction, Antioxidant Capacities and Α-Amylase and Α-Glucosidase Inhibition of Clematis flammula and Periploca angustifolia Abstract Phytochemicals are extensively found at different levels in many medicinal plants.
Khaled Athmouni, Taheni Belghith
openaire   +1 more source