Identifying patient characteristics predictive of treatment response is crucial for optimizing type 2 diabetes outcomes. Using data from three phase 2/3 imeglimin trials in Japan, this analysis applied machine learning to determine characteristics associated with HbA1c improvement.
Katsuhiko Hagi +4 more
wiley +1 more source
Model for the non‐PTS utilization of manno‐oligosaccharides by Cellvibrio japonicus. The Mgp130A and EpiA enzymes are essential for the utilization of mannose residues. ABSTRACT Manno‐oligosaccharides and their metabolism play important roles in gut health, pharmaceutical development, and renewable chemical production.
Jessica K. Novak, Jeffrey G. Gardner
wiley +1 more source
Identification of Selective α-Glucosidase Inhibitors via Virtual Screening with Machine Learning. [PDF]
Guo F +10 more
europepmc +1 more source
Biomass degrading enzymes from Penicillium – cloning and characterization [PDF]
Krogh, Kristian Bertel Rømer
core
Summary Obtaining sufficient light for photosynthesis and avoiding desiccation are two key challenges faced by seedlings during early establishment. Perception of light quality via specialised photoreceptors signals the availability of sunlight for photosynthesis.
Mathilda Gustavsson +3 more
wiley +1 more source
Phytochemical constituents of <i>Hydrangea macrophylla</i> var. <i>acuminata</i> leaves and their inhibitory activity against PTP1B and α-glucosidase. [PDF]
Pham TL +4 more
europepmc +1 more source
A sequential multi‐strain inoculation approach for designing functional Sicilian table olives
Abstract BACKGROUND The exploitation of microbial strains with advanced technological traits is a pivotal step in enhancing the production of table olives and meeting consumers' demands. RESULTS Here, a multi‐step approach involving the sequential addition of a Lactiplantibacillus plantarum (namely C11C8) starter strain and a Lacticaseibacillus ...
Irene M Zingale +10 more
wiley +1 more source
Porcine serum maltase-glucoamylase: structure, kinetics, and inhibition. [PDF]
Watanabe K +7 more
europepmc +1 more source
In vitro α-glucosidase inhibition, molecular dynamics and docking study of phenyl carbamoyl methoxy thiosemicarbazone derivatives as potential anti-diabetic agents. [PDF]
Valadbeigi S +4 more
europepmc +1 more source
Synthesis and pharmacological profiling of cis-1-amino-2-indanol derivatives as α-glucosidase inhibitors. [PDF]
Khan S +11 more
europepmc +1 more source

