Results 91 to 100 of about 7,137 (171)

Potato glycoside alkaloids exhibit antifungal activity by regulating the tricarboxylic acid cycle pathway of Fusarium solani

Frontiers in Microbiology
Fusarium solani is a pathogenic fungus that causes significant harm, leading to crop yield reduction, fruit quality reduction, postharvest decay, and other diseases.
Chongqing Zhang, Wei Chen, Bin Wang, Yupeng Wang, Nan Li, Ruiyun Li, Yuke Yan, Yuyan Sun, Jing He, Jing He   +9 more
doaj   +1 more source

Review of Alpha-Ketoglutaric Acid (AKGA) Hydrazine and Monomethylhydrazine (MMH) Neutralizing Compound [PDF]

The Johnson Space Center (JSC) White Sands Test Facility (WSTF) and NASA Engineering and Safety Center (NESC) were requested by NASA Associate Administrator for Space Operations to perform an evaluation of a proposed hydrazine/monomethylhydrazine (MMH ...
Beeson, Harold D., Dibbern, Andreas W., Giordano, Thomas J., Greene, Benjamin   +3 more
core   +1 more source

Structural insights into the production of 3-hydroxypropionic acid by aldehyde dehydrogenase from Azospirillum brasilense [PDF]

, 2017
3-Hydroxypropionic acid (3-HP) is an important platform chemical to be converted to acrylic acid and acrylamide. Aldehyde dehydrogenase (ALDH), an enzyme that catalyzes the reaction of 3-hydroxypropionaldehyde (3-HPA) to 3-HP, determines 3-HP production ...
A Vagin, AK Forrest, BW Matthews, C Rathnasingh, E Celinska, E Krissinel, F Barbirato, F Barbirato, GN Murshudov, GP da Silva, HG Lim, HS Chu, JE Jo, KNG Valdehuesa, LH Luo, M Hugler, M Hugler, M Su, NA Sophos, O Trott, P Emsley, RG Forage, RK Saxena, S Ashok, S Nitayavardhana, S Watanabe, SM Raj, SM Raj, T Toraya, V Kumar, V Kumar, Y Ko, Y Li, Z Otwinowski   +33 more
core   +1 more source

Ancestral function and diversification of a horizontally acquired oomycete carboxylic acid transporter [PDF]

, 2018
This is the author accepted manuscript. The final version is available from OUP via the DOI in this recordHorizontal gene transfer (HGT) can equip organisms with novel genes, expanding the repertoire of genetic material available for evolutionary ...
Miles, DC, Milner, DS, Richards, TA, Savory, FR   +3 more
core   +1 more source

Cloning of a novel gene from Penicillium oxalicum I1 which in Escherichia coli enhances the secretion of acetic acid

Biotechnologie, Agronomie, Société et Environnement, 2018
Description of the subject. Organic acids play an important role in the conversion of insoluble ions into soluble ones in soil. Heterologous overexpression of a single gene in a cell is the optimal strategy for increasing the secretion of organic acids ...
Xue, L., Chang-xiong, Z., Ming-bo, G.
doaj  

Identifying the target, mechanism, and agonist of α-ketoglutaric acid in delaying mesenchymal stem cell senescence

Cell Reports
Summary: α-ketoglutaric acid (AKG), a tricarboxylic acid cycle metabolite central to aerobic metabolism and longevity, retains unresolved anti-aging protein targets.
Zhao Cui, Jiameng Li, Caifeng Li, Shiwen Deng, Wei Liu, Tong Lei, Junxian Cao, Ziyi Wang, Xiaoxu Wang, Shuhua Ma, Yinhua Zhu, Hongjun Yang, Peng Chen   +12 more
doaj   +1 more source

α-Ketoglutaric acid: a new chance for male fertility preservation. [PDF]

Life Metab, 2022
Dong F, Li W.
europepmc   +1 more source

α-Ketoglutaric acid ameliorates hyperglycemia in diabetes by inhibiting hepatic gluconeogenesis via serpina1e signaling. [PDF]

Sci Adv, 2022
Yuan Y, Zhu C, Wang Y, Sun J, Feng J, Ma Z, Li P, Peng W, Yin C, Xu G, Xu P, Jiang Y, Jiang Q, Shu G.   +13 more
europepmc   +1 more source

Integrated morpho-physiological, transcriptomic and metabolomic data to reveal the differential chilling defense mechanisms of two ecologically diverged species of Forsythia

Horticultural Plant Journal
Long-term niche differentiation will lead to the evolution of diverse adaptive strategies for species in diverse environments. The present study selected two Forsythia species, Forsythia mandshurica (Fm)—which naturally occurs in a cold temperate zone ...
Jian Cui, Rong Wu, Xiaoyang Sun, Yong Li
doaj   +1 more source

Dose- and Sex-Dependent Changes in Hemoglobin Oxygen Affinity by the Micronutrient 5-Hydroxymethylfurfural and α-Ketoglutaric Acid. [PDF]

Nutrients, 2021
Woyke S, Mair N, Ortner A, Haller T, Ronzani M, Rugg C, Ströhle M, Wintersteiger R, Gatterer H.   +8 more
europepmc   +1 more source