Results 41 to 50 of about 7,137 (171)

Impact of soil warming on the plant metabolome of Icelandic grasslands [PDF]

, 2017
Altres ajuts: Scholarly Studies programme of the Smithsonian Institution, projects LM2015061 and LO1415 of the Ministry of Education, Youth and Sports of the Czech Republic, and the Research Foundation-Flanders (FWO aspirant grant to N.L.).Climate change
Ayala-Roque, Marta, Bartrons Vilamala, Mireia, Gargallo-Garriga, Albert, Granda, Víctor, Janssens, Ivan A., Leblans, Niki I. W., Oravec, Michal, Peñuelas, Josep, Sardans i Galobart, Jordi, Sigurdsson, Bjarni D., Urban, Otmar   +10 more
core   +2 more sources

Analysis of Regulatory Mechanism of AcrB and CpxR on Colistin Susceptibility Based on Transcriptome and Metabolome of Salmonella Typhimurium

Microbiology Spectrum, 2023
With the increasing and inappropriate use of colistin, the emerging colistin-resistant isolates have been frequently reported during the last few decades.
Ya-Jun Zhai, Pei-Yi Liu, Xing-Wei Luo, Jun Liang, Ya-Wei Sun, Xiao-Die Cui, Dan-Dan He, Yu-Shan Pan, Hua Wu, Gong-Zheng Hu   +9 more
doaj   +1 more source

Improved metabolic health alters host metabolism in parallel with changes in systemic xeno-metabolites of gut origin. [PDF]

PLoS ONE, 2014
Novel plasma metabolite patterns reflective of improved metabolic health (insulin sensitivity, fitness, reduced body weight) were identified before and after a 14-17 wk weight loss and exercise intervention in sedentary, obese insulin-resistant women. To
Caitlin Campbell, Dmitry Grapov, Oliver Fiehn, Carol J Chandler, Dustin J Burnett, Elaine C Souza, Gretchen A Casazza, Mary B Gustafson, Nancy L Keim, John W Newman, Gary R Hunter, Jose R Fernandez, W Timothy Garvey, Mary-Ellen Harper, Charles L Hoppel, John K Meissen, Kohei Take, Sean H Adams   +17 more
doaj   +1 more source

Metabolomics Reveals Changes in Metabolite Profiles among Pre-Diapause, Diapause and Post-Diapause Larvae of Sitodiplosis mosellana (Diptera: Cecidomyiidae)

Insects, 2022
Sitodiplosis mosellana, a notorious pest of wheat worldwide, copes with temperature extremes during harsh summers and winters by entering obligatory diapause as larvae. However, the metabolic adaptive mechanism underlying this process is largely unknown.
Qitong Huang, Qian Ma, Fangxiang Li, Keyan Zhu-Salzman, Weining Cheng   +4 more
doaj   +1 more source

A Cryoprotectant‐Compatible Nanoporous Platform for Stable and Scalable Delivery of Biopharmaceuticals

Advanced Materials, EarlyView.
A cryoprotectant‐compatible nanoporous platform enables ambient‐stable and scalable delivery of gene editing therapeutics. By combining hierarchical pore architecture with optimized lyophilization chemistry, the system preserves Cas9‐RNP activity post‐freeze‐drying.
Sian Lee, Seongchan Kim, Jooyeun Chong, Min‐gyeong Kim, Kayeong Lim, Nan‐Ee Lee, Jahyun Koo, Jiheong Kang, Hyojin Lee   +8 more
wiley   +1 more source

Field application of the mycorrhizal fungus Rhizophagus irregularis increases the yield of wheat crop and affects soil microbial functionalities [PDF]

, 2015
The aim of this study was to test the impact of Rhizophagus irregularis, an arbuscular mycorrhizal fungus (AMF), on durum wheat growth and soil microbial functionalities in a field inoculation trial conducted in Morocco. The results showed that i) the R.
Duponnois, Robin, Hafidi, Mohamed, Maghraoui, Tasnime, Oufdou, Khalid, Prin, Yves, Sanguin, Hervé, Thioulouse, Jean, Wahbi, Sanâa   +7 more
core   +3 more sources

Nanoparticle‐Mediated Immunometabolic‐Epigenetic Remodeling Enhances Schwann Cell‐Macrophage Interaction for Sciatic Nerve Regeneration

Advanced Science, EarlyView.
A biomimetic Prussian White nanoparticle (PW) is engineered to achieve long‐term local retention and orchestrate immunometabolic‐epigenetic remodeling for sciatic nerve regeneration. PW directly targets hexokinase 2 to suppress glycolysis, thereby elevating α‐ketoglutarate and driving Kdm4a/b‐mediated demethylation of H3K9me3.
Wenying Xu, Rongrong Wu, Zhicheng Liu, Hongyu Yan, Huan Zhang, Yuanyi Zheng, Xiaojun Cai   +6 more
wiley   +1 more source

Ammonia toxicity: from head to toe? [PDF]

, 2016
Ammonia is diffused and transported across all plasma membranes. This entails that hyperammonemia leads to an increase in ammonia in all organs and tissues.
Dasarathy, Srinivasan, Mookerjee, Rajeshwar P., Ott, Peter, Rackayova, Veronika, Rangroo Thrane, Vinita, Rose, Christopher, Vairappan, Balasubramaniyan   +6 more
core   +1 more source

Metabolic regulation by biomaterials in osteoblast

Frontiers in Bioengineering and Biotechnology, 2023
The repair of bone defects resulting from high-energy trauma, infection, or pathological fracture remains a challenge in the field of medicine. The development of biomaterials involved in the metabolic regulation provides a promising solution to this ...
Zhengyang Kang, Zhengyang Kang, Zhengyang Kang, Bin Wu, Luhui Zhang, Xinzhi Liang, Dong Guo, Shuai Yuan, Denghui Xie, Denghui Xie, Denghui Xie   +10 more
doaj   +1 more source

Alterations in Metabolites Associated With Umbilical Cord Blood in Monozygotic Twins Discordant for Congenital Heart Disease

Pediatric Discovery, EarlyView.
This study found that the metabolomic signature of umbilical venous cord blood in congenital heart disease (CHD) differs from that of healthy monozygotic (MZ) co‐twins. Dysregulation of metabolic pathways like glucose, lipid, and amino acid metabolism, along with altered metabolites, helps understand CHD predisposition.
Fang Xiang, Xiao Yuan, Yi Yang, Philip N. Baker, Mark D. Kilby, Chao Tong, Xi Yuan   +6 more
wiley   +1 more source