Results 21 to 30 of about 33,504 (118)

Antitumor Activity of α-Linolenic Acid-Paclitaxel Conjugate Nanoparticles: In vitro and in vivo

International Journal of Nanomedicine, 2021
Mei-Qi Xu,1,2 Yan-Li Hao,1,2 Jing-Ru Wang,1,2 Zhuo-Yue Li,1,2 Hui Li,1 Zhen-Han Feng,1,2 Hui Wang,1,2 Jing-Wen Wang,1,2 Xuan Zhang1,2 1Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, School of Pharmaceutical Sciences ...
Xu MQ, Hao YL, Wang JR, Li ZY, Li H, Feng ZH, Wang H, Wang JW, Zhang X   +8 more
doaj  

Specific phospholipid fatty acid composition of brain regions in mice: effects of n–3 polyunsaturated fatty acid deficiency and phospholipid supplementation

Journal of Lipid Research, 2000
: This study examined the effects of dietary α-linolenic acid deficiency followed or not by supplementation with phospholipids rich in n–3 polyunsaturated fatty acid (PUFA) on the fatty acid composition of total phospholipids in 11 brain regions.
Isabelle Carrié, Michel Clément, Dominique de Javel, Henriette Francès, Jean-Marie Bourre   +4 more
doaj   +1 more source

Alpha-Linolenic Acid Attenuates Inflammatory Response in LPS-stimulated Macrophages by Regulating TLR4/MyD88/NF-κB Signaling Pathway

Shipin gongye ke-ji
Omega-3 fatty acids have natural anti-inflammatory properties, and α-linolenic acid (ALA) is an essential ω-3 fatty acid. In order to elucidate its anti-inflammatory mechanism in vitro, lipopolysaccharide (LPS) was used to stimulate macrophages to ...
Ruixin CAI, Xiaodie CHEN, Haibin ZHU, Yushun QIAN, Jianhua XIE, Mingyue SHEN   +5 more
doaj   +1 more source

Desaturation and chain elongation of [1-14C]mono-trans isomers of linoleic and α-linolenic acids in perfused rat liver

Journal of Lipid Research, 1998
Trans polyunsaturated fatty acids are produced during heat treatment of oils, such as deodorization and frying. The detailed metabolic pathways of these trans isomers are not fully understood. In the present work, the desaturation and chain elongation of
Lionel Bretillon, Jean-Michel Chardigny, Jean-Pierre Noël, Jean-Louis Sébédio   +3 more
doaj   +1 more source

Lipid composition of the Amazonian ‘Mountain Sacha Inchis’ including Plukenetia carolis-vegae Bussmann, Paniagua & C.Téllez

Scientific Reports, 2022
Several Amazonian species of Plukenetia are remarkably rich sources of polyunsaturated fatty acids, in particular α-linolenic acid. The lipid composition of the large-seeded, recently described ‘Mountain Sacha Inchi’ Plukenetia carolis-vegae is reported ...
Nete Kodahl, Heidi Blok Frandsen, Henrik Lütken, Iben Lykke Petersen, Nelly Judith Paredes Andrade, Carmen García-Davila, Marten Sørensen   +6 more
doaj   +1 more source

α-Linolenic acid prevents endoplasmic reticulum stress-mediated apoptosis of stearic acid lipotoxicity on primary rat hepatocytes

Lipids in Health and Disease, 2011
Aims Lipid accumulation in non-adipose tissues leads to cell dysfunction and apoptosis, a phenomenon known as lipotoxicity. Unsaturated fatty acids may offset the lipotoxicity associated with saturated fatty acids.
Shi Hongyang, Yang Xia, Dong Lei, Zhang Yong, Zhang Li   +4 more
doaj   +1 more source

Habitual Fish Consumption, n‐3 Fatty Acids, and Nuclear Magnetic Resonance Lipoprotein Subfractions in Women

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Supplementation with omega‐3 (n‐3) fatty acid or dietary fish may protect against atherosclerosis, but the potential mechanisms are unclear.
Nuria Amigó, Akintunde O. Akinkuolie, Stephanie E. Chiuve, Xavier Correig, Nancy R. Cook, Samia Mora   +5 more
doaj   +1 more source

Fatty acids composition of fruits of selected Central European sedges (Carex L. Cyperaceae)

Grasas y Aceites, 2010
Fatty acids in the fruits of 13 sedge species (Carex L., Cyperaceae) were analyzed. The oil contents in the fruits of the studied sedges ranged from 3.73 and 46.52%. In the studied fruit oils 14 different fatty acids were identified. The main unsaturated
Anna Bogucka-Kocka, Magdalena Janyszek
doaj   +1 more source

Relative quantification of deuterated omega-3 and -6 fatty acids and their lipid turnover in PC12 cell membranes using TOF-SIMS

Journal of Lipid Research, 2018
Understanding FA metabolism and lipid synthesis requires a lot of information about which FAs and lipids are formed within the cells. We focused on the use of deuterated substrates of 100 μM α-linolenic acid and linoleic acid to determine the relative ...
Mai H. Philipsen, Sanna Sämfors, Per Malmberg, Andrew G. Ewing   +3 more
doaj   +1 more source

Fatty acid chemistry of Atrichum undulatum and Hypnum andoi [PDF]

Hemijska Industrija, 2012
The fatty acid composition of the moss species Atrichum undulatum (Hedw.) P. Beauv. (Polytrichaceae) and Hypnum andoi A.J.E. Sm. (Hypnaceae) collected in winter time were analyzed by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-
Pejin Boris, Vujisić Ljubodrag, Sabovljević Marko, Tešević Vele, Vajs Vlatka   +4 more
doaj   +1 more source