Results 81 to 90 of about 10,932 (154)

The Synthetic Melanocortin Agonist NDP‐MSH Ameliorates THSD7A‐Associated Membranous Nephropathy in an Active Immunization Mouse Model

The FASEB Journal, Volume 40, Issue 13, 15 July 2026.
Active immunization with recombinant THSD7A in mice induces autoreactive B cell activation and differentiation into CD138+ antibody‐secreting cells, leading to the production of anti‐THSD7A autoantibodies, glomerular immune injury and proteinuria, characteristic of membranous nephropathy. NDP‐MSH treatment modulates the MITF/IRF4 axis in primed B cells,
Mingzhuo Zhang, Mengxuan Chen, Yan Ge, William Gunning, Rujun Gong   +4 more
wiley   +1 more source

Alpha-melanocyte-stimulating hormone contributes to an anti-inflammatory response to lipopolysaccharide

Molecular Metabolism
Objective: During infection, metabolism and immunity react dynamically to promote survival through mechanisms that remain unclear. Pro-opiomelanocortin (POMC) cleavage products are produced and released in the brain and in the pituitary gland.
R.P. Reynolds, R.R. Fan, A. Tinajero, X. Luo, S.C. Huen, T. Fujikawa, S. Lee, A. Lemoff, K.G. Mountjoy, J.K. Elmquist   +9 more
doaj   +1 more source

Anhydrous Alum Inhibits α-MSH-Induced Melanogenesis by Down-Regulating MITF via Dual Modulation of CREB and ERK. [PDF]

Int J Mol Sci, 2023
In KR, Kang MA, Kim SD, Shin J, Kang SU, Park TJ, Kim SJ, Lee JS.   +7 more
europepmc   +1 more source

A Dual‐Memory Ferroelectric Transistor Emulating Synaptic Metaplasticity for High‐Speed Reservoir Computing

Advanced Electronic Materials, Volume 12, Issue 13, 6 July 2026.
A CMOS‐compatible ferroelectric transistor harnesses the interplay between stable gate polarization memory and volatile non‐quasi‐static channel charge dynamics to emulate how biological synapses regulate their own plasticity. This brain‐inspired dual‐memory mechanism, realized in a single device, enables a physical reservoir computer that solves ...
Yifan Wang, Muhammad Sakib Shahriar, Salma Soliman, Noah Vaillancourt, Lance Fernandes, Andrea Padovani, Asif Islam Khan, Md Sakib Hasan, Raisul Islam   +8 more
wiley   +1 more source

Blockage of HSP90 and IDO1 pathway by α-MSH modified nanoelicitor to dual-facilitate mild photothermal therapy. [PDF]

Pharm Sci Adv, 2023
Fu S, Ma Q, Li J, Wang Y, Yang C, Gu P, Zhang W, Liu Y, Zhang N.   +8 more
europepmc   +1 more source

Activational Effects of Gonadal Hormones on Social Reward Motivation in Adolescence and Adulthood in Female and Male Long–Evans Rats

Developmental Psychobiology, Volume 68, Issue 4, July 2026.
ABSTRACT There are age and sex differences in the processing of social reward, although the basis for these differences is not well established. We previously found greater social motivation at P50 (postpubertal adolescence) than at P70 (adulthood), and that female rats showed greater social motivation than male rats.
S. H. Murray, A. M. Randell, F. S. E. Krajcovic, B. C. J. Fletcher, C. M. McCormick   +4 more
wiley   +1 more source

Neurodevelopmental Consequences Induced by Early‐Life Lead Exposure Through Disruption of Neurotransmitter Pathways and Molecular Mechanisms: A Systematic Review

Developmental Neurobiology, Volume 86, Issue 3, July 2026.
ABSTRACT Lead is a toxic heavy metal with significant health risks, as maternal lead exposure during pregnancy disrupts fetal neural development through placental transfer, leading to persistent neurological, developmental, and long‐term health consequences in the progeny.
P. Harshitha, Aluru Parithathvi, Kamalesh Dattaram Mumbrekar, Herman Sunil Dsouza   +3 more
wiley   +1 more source

Corrigendum to "Blockage of HSP90 and IDO1 pathway by α-MSH modified nanoelicitor to dual-facilitate mild photothermal therapy" [Pharmaceut. Sci. Res. 1 (2023) 100009]. [PDF]

Pharm Sci Adv, 2023
Fu S, Ma Q, Li J, Wang Y, Yang C, Gu P, Zhang W, Liu Y, Zhang N.   +8 more
europepmc   +1 more source

Food and Medicinal Homologous Substances in Sleep Disorders Improvement: Current Advances and Future Perspectives

Food Frontiers, Volume 7, Issue 4, July 2026.
The schematic diagram illustrating the improvement mechanisms of six typical FMH substances and their main active ingredients in different sleep disorders. ABSTRACT Sleep integrates many brain and peripheral processes, profoundly influencing well‐being.
Wenjing Wen, Qili Li, Chenghao Lv, Jing Wen, Yihan Zhang, Yuhang Yi, Tao Li, Fang Wang, Yibo Luo, Si Qin   +9 more
wiley   +1 more source

Exploring the Usability of α-MSH-SM-Liposome as an Imaging Agent to Study Biodegradable Bone Implants In Vivo. [PDF]

Int J Mol Sci, 2023
Riyaz S, Helmholz H, Penate Medina T, Peñate Medina O, Will O, Sun Y, Wiese B, Glüer CC, Willumeit-Römer R.   +8 more
europepmc   +1 more source