Co-Existence of tau and α-synuclein pathology in fetal graft tissue at autopsy: A case report
, 2020 Abbie S. Ornelas +6 more
openalex +2 more sources
The Effects of Lipids on α-Synuclein Aggregation In Vitro [PDF]
, 2023 Jennifer Ramirez +3 more
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Mass Spectrometry Structural Proteomics Enabled by Limited Proteolysis and Cross‐Linking
Mass Spectrometry Reviews, EarlyView.ABSTRACT The exploration of protein structure and function stands at the forefront of life science and represents an ever‐expanding focus in the development of proteomics. As mass spectrometry (MS) offers readout of protein conformational changes at both the protein and peptide levels, MS‐based structural proteomics is making significant strides in the
Haiyan Lu +4 more
wiley +1 more source
Mass Spectrometry Reviews, EarlyView.ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley +1 more source
Is efficiency of protein incorporations governed by membrane properties? An α -synuclein and ceramide-1-phosphate investigation [PDF]
Dominik Drabik +3 more
openalex +1 more source
DJ-1 and α-synuclein in human cerebrospinal fluid as biomarkers of Parkinson’s disease [PDF]
, 2010 Zhen Hong +17 more
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Comparing α-Synuclein Fibrils Formed in the Absence and Presence of a Model Lipid Membrane: A Small and Wide-Angle X-Ray Scattering Study [PDF]
, 2022 Marija Dubackic +3 more
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Prodromal Lewy Body Symptoms and α‐Synuclein Seeding in Idiopathic Olfactory Dysfunction
Movement Disorders Clinical Practice, EarlyView.Abstract Background Early identification of pathological α‐synuclein deposition (αSynD) may improve understanding of Lewy body disorder (LBD) progression and enable timely disease‐modifying treatments. Objectives We investigated αSynD using a seed amplification assay and assessed prodromal LBD symptoms in individuals with idiopathic olfactory ...
Oskar Hoffmann McWilliam +15 more
wiley +1 more source
Effect of Mutant α-Synuclein on Dopamine Homeostasis in a New Human Mesencephalic Cell Line [PDF]
, 2002 Julie Lotharius +5 more
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Movement Disorders Clinical Practice, EarlyView.Abstract Background Research on Parkinson's disease (PD) heterogeneity may inform clinical prognosis. There is currently no fully validated PD subtype classification system. Objectives We aimed at assessing the prognostic relevance of a data‐driven PD subtype classification system.
Deepa Dash +7 more
wiley +1 more source