Results 211 to 220 of about 83,002 (289)

Simultaneous Assessment of Intracranial Artery and Paravascular CSF Pulsation Using 3D Whole‐Brain Diffusion‐Prepared Cine bSSFP (DECAF) MRI

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To propose a noninvasive and quantitative MRI approach to simultaneously assessing intracranial artery pulsation and paravascular cerebrospinal fluid (CSF) pulsation in the human brain. Methods We developed a 3D whole‐brain Diffusion‐prepared Cine bSSFP (DECAF) MRI technique, with improved motion‐sensitized driven‐equilibrium providing
Chang Ni, Xiangjian Hou, SeyyedKazem HashemizadehKolowri, Seong‐Eun Kim, Qiuting Wen, Nicholas A. Frost, J. Scott McNally, Chun Yuan, Xiaodong Ma   +8 more
wiley   +1 more source

Lack of Cerebrospinal Fluid α‐Synuclein Seeding in VPS35 D620N‐ and LRRK2 Y1699C‐Linked Parkinson's Disease

Movement Disorders, EarlyView.
Letizia Santinelli, Neringa Pratuseviciute, Lara M. Lange, Teresa Kleinz, Norbert Brüggemann, Linn Streubel‐Gallasch, Meret Möller, Alexander Zimprich, Christof Brücke, Jean‐Marc Good, Norman Griebner, Shalini Padmanabhan, Philip Seibler, Peter Bauer, Wim Vandenberghe, Esther Sammler, Cornelis Blauwendraat, Christine Klein, Max Borsche   +18 more
wiley   +1 more source

Mechanistic Insights of Zonisamide in Parkinson's Disease: A Systematic Review

Neurology and Clinical Neuroscience, EarlyView.
ABSTRACT Zonisamide is an antiepileptic agent used as adjunctive therapy for Parkinson's Disease in Japan and studied more selectively elsewhere. Preclinical and early translational studies suggest that zonisamide may modulate several pathways relevant to Parkinson's Disease pathobiology, including dopaminergic neurotransmission, oxidative stress ...
Justin Kim, Nathan Chan, Jilai Zhao, Tien K. Khoo   +3 more
wiley   +1 more source

Tubulin transforms Tau and α-synuclein condensates from pathological to physiological. [PDF]

Nat Commun
Lucas L, Tsoi PS, Quan MD, Choi KJ, Ferreon JC, Ferreon ACM.   +5 more
europepmc   +1 more source

Pleiotropic effects of variants in dementia genes in Parkinson disease [PDF]

, 2018
Benitez, Bruno A, Budde, John, Cooper, Breanna, Cruchaga, Carlos, David, Albert A, Diez-Fairen, Monica, Dube, Umber, Fernandez, Maria V, Ibanez, Laura, Ortega-Cubero, Sara, Pastor, Pau, Perlmutter, Joel S   +11 more
core   +2 more sources

Exercise, exerkines, and muscle–brain crosstalk in Parkinson's disease

Neuroprotection, EarlyView.
Abstract Parkinson's disease (PD) is a progressive neurodegenerative disorder with motor and non‐motor symptoms, driven by dopaminergic loss and α‐synuclein accumulation. Beyond neurodegeneration, growing evidence highlights skeletal muscle health as a key determinant of prognosis, with sarcopenia and frailty contributing to greater disability, fall ...
Salomón Páez‐García, Edgar Alvarado, Alejandro Cuevas, Laura Valverde, Eduardo Salinas, Kevin O'Hara‐Veintimilla, María Cruz Rodríguez‐Oroz, Miguel Germán Borda   +7 more
wiley   +1 more source

Correction to "Aggregation and Propagation of α-Synuclein in Parkinson's Disease: A Bibliometric Perspective". [PDF]

Brain Behav
europepmc   +1 more source

circFKBP8(5S,6)-encoded protein modulates α-synuclein expression in SH-SY5Y cells. [PDF]

Mol Biol Rep
Uzoechina J, Zhang Z.
europepmc   +1 more source

The Effects of Prolyl Oligopeptidase Inhibition in α-Synuclein Based Mouse Models of Parkinson's Disease

, 2020
openaire   +1 more source

Exploring Linalool‐Based Phytotherapy for Excitatory/Inhibitory Imbalance in Alzheimer's Disease: A Review of Lavender and Cannabis Therapeutic Effects on Sleep, Seizures, and Cognition

Phytotherapy Research, EarlyView.
Schematic overview of the proposed neuromodulatory actions of linalool in Alzheimer's disease. Through multi‐target effects on oxidative stress, amyloid aggregation, GABAergic and glutamatergic signaling, linalool may restore excitatory/inhibitory balance.
Ilaria Piccialli, Giovanni Roviello, Giorgia Magliocca, Emilia Esposito, Anna Pannaccione   +4 more
wiley   +1 more source