Results 101 to 110 of about 1,044,639 (194)

Intratumoral and Peritumoral Functional Connectivity Reveals Network‐Level Signatures of Glioma

MedComm, Volume 7, Issue 11, November 2026.
Using resting‐state fMRI in 306 glioma patients, this study maps individualized intra‐ and peritumoral functional networks. Novel metrics (RIFR, RPTR) quantify tumor‐related network remodeling, correlating with pathology, structure, cognition, and survival. A prognostic model incorporating these network features achieves an AUC of 0.90.
Hongbo Bao, Yan Bai, Jie Hu, Wencai Ding, Jiacheng Lai, Andrew Zalesky, Ye Ella Tian, Yanmei Tie, Janet Mei, Shengyu Fang, Xing Fan, Licia P. Luna, Craig K. Jones, Jianxun Ren, Weigang Cui, Jiadong Yan, Zeya Yan, Zihan Wang, Renwu Zhang, Zhonghua Lv, Yihang Jiao, Tao Jiang, Peng Liang, Haris I. Sair, Yinyan Wang   +24 more
wiley   +1 more source

Genotypic‐Phenotypic Correlations in Non‐HbE β‐Thalassemia Intermedia: A Geographic Systematic Review

Molecular Genetics &Genomic Medicine, Volume 14, Issue 11, November 2026.
β‐Thalassemia intermedia exhibits distinct region‐specific molecular patterns shaped by three interacting genetic axes: β‐globin mutation severity, HbF‐inducing modifiers, and α‐globin gene dosage. Mediterranean populations are predominantly mutation‐driven, Middle Eastern populations rely on HbF compensation, and Asian populations are governed by ...
Kavindya Fernando, Shiromi Perera, Anuja Premawardhena   +2 more
wiley   +1 more source

Molecular and Hematological Characterization of α-Thalassemia in Denizli Province

Acta Haematologica Oncologica Turcica
Aim: Alpha thalassemia, a common monogenic disorder, occurs with defective synthesis of the α-globin chain and has a very wide clinical spectrum depending on the disorders in the globin genes.
Derya Karaer, Tuba Uğurlu Er, Nevin Alayvaz Aslan, Taner Durak   +3 more
doaj   +1 more source

Screening for (-(SEA)) α-globin gene deletion in β-thalassemia carriers and prevention of hydrops fetalis

, 2000
In Southeast Asia, where thalassemia is prevalent, heterozygous carriers of both β-thalassemia mutation and the (-(SEA)) α-globin gene deletion are encountered.
Ma, ESK, Chan, GCF, Yu Lung Lau, Shau Yin Ha, Li Chong Chan, Chan, AYY   +5 more
core  

The prevalence and molecular spectrum of α- and β-globin gene mutations in 14,332 families of Guangdong Province, China.

PLoS ONE, 2014
ObjectiveTo reveal the familial prevalence and molecular variation of α- and β-globin gene mutations in Guangdong Province.MethodsA total of 40,808 blood samples from 14,332 families were obtained and analyzed for both hematological and molecular ...
Aihua Yin, Bing Li, Mingyong Luo, Longchang Xu, Li Wu, Liang Zhang, Yuanzhu Ma, Tingting Chen, Shuang Gao, Juqing Liang, Hao Guo, Danqing Qin, Jicheng Wang, Tenglong Yuan, Yixia Wang, Wei-wei Huang, Wen-Fei He, Yanxia Zhang, Chang Liu, Sujian Xia, Qingshan Chen, Qingguo Zhao, Xiaozhuang Zhang   +22 more
doaj   +1 more source

Racial disparities in anaemia associated with paediatric chronic kidney disease

British Journal of Haematology, EarlyView.
Manya Raina, Shay Tanna, Brandon H. Lee, Bradley A. Warady   +3 more
wiley   +1 more source

The role of iron in normal and impaired testicular function

Andrology, Volume 14, Issue 8, Page 2373-2387, November 2026.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer, Esther G. Meyron‐Holtz, Andreas Meinhardt   +2 more
wiley   +1 more source

Proportions of studied characteristics (malaria prevalence, HbE, G6PD deficiency, α-thalassemia, β-thalassemia), by village and ethnic group (A) and by linguistic family (B).

, 2016
Proportions of studied characteristics (malaria prevalence, HbE, G6PD deficiency, α-thalassemia, β-thalassemia), by village and ethnic group (A) and by linguistic family (B).
Saovaros Svasti (164396), Pitsinee Inti (848195), Jatupol Kampuansai (589980), Pathrapol Lithanatudom (848194), Kriangkrai Chawansuntati (230380), Daoroong Kangwanpong (589988), Jiraprapa Wipasa (230369), Suthat Fucharoen (164423)   +7 more
core   +1 more source

Sickle cell anaemia in Cameroon : co-inheritance of α-thalassemia, HBB gene haplotypes, clinical & haematological characterisations [PDF]

, 2015
Background: Although sickle cell anaemia (SCA) is genetically characterised by a single point mutation, patients can manifest varying degrees of clinical severity due to various genetic modulators that affect the phenotype of this disease.
Rumaney, Maryam
core   +1 more source

Application of electrospray triple quadrupole mass spectrometry in assessing thalassemia in a population

Indian Journal of Pathology and Microbiology
Introduction: Thalassemia is widely prevalent in Asian countries and the Middle East region of the world. While the prevalence of α thal is around 5-20% in the population, the incidence of β thal is around 3-4%.
Deepalakshmi D. Putchen, Athira Nambiar, Ashwini Bijur, Nelson Amirtharaj, Sujay Ramaprasad   +4 more
doaj   +1 more source