Results 121 to 130 of about 1,044,639 (194)

α-, β-thalassaemia alleles and their distribution among the three regions in Jiangxi province.

, 2014
aThese numbers include silent heterozygous mutation, α-thalassemia trait, Hb H disease and α-thalassemia compound β-thalassemia;bThese numbers include β-thalassemia trait and α-thalassemia compound β-thalassemia.
Wen-Yu Li (593834), Min Lin (17652), Xiao-Fen Zhan (285487), Tian-Yu Zhong (593832), Jiao-Ren Wu (285484), Yi-Guo Chen (593833), Hui Yang (91136), Li-Ye Yang (285504), Xiao-Mei Hu (418370), Xin Tong (48765), Hui-Tian Yang (285489), Jian-Zhong Wang (213265), Zhao-Yun Luo (331441), Fen Lin (285486), Rong Hu (153724)   +14 more
core   +1 more source

Molecular and hematological characterization of thalassemia and hemoglobinopathies among pediatric patients in northern Lao People’s Democratic Republic

Scientific Reports
Thalassemia and hemoglobinopathies are highly prevalent in the Lao People’s Democratic Republic (Lao PDR). Luang Prabang Province represents an ethnically diverse area with a high burden of pediatric anemia, but the molecular and hematological ...
Volapheth Kanyasone, Pichpimon Pakpuak, Supitsaraporn Satewin, Anupong Pansuwan, Kritsada Singha, Attawut Chaibunruang, Hataichanok Srivorakun, Supan Fucharoen, Annkham Thammaseng, Sengmany Sengphachan, Hame Thiphalack, Anousine Phonedala, Supawadee Yamsri   +12 more
doaj   +1 more source

Diagnosis of α-thalassemia using droplet digital PCR

Most α-thalassemia occurs due to a large deletion in the α-globin gene. Common α-thalassemia with known mutations, such as Southeast Asian (SEA) type is readily diagnosed by Gap-PCR.
Mori, Kentaro, 山﨑, 隆弘, Ohto, Fukumi, Kimoto, Masafumi, Amao, Yuki, Hattori, Yukio, Mella, Ferania, 末廣, 寛, 山城, 安啓, Ogata, Shizuka   +9 more
core  

Association between α-thalassemia heterozygote (_α/αα) and Hemoglobin AS including interaction terms.

, 2018
Association between α-thalassemia heterozygote (_α/αα) and Hemoglobin AS including interaction terms.
Grace Ndeezi (491009), Charles Karamagi (351710), Anne Katahoire (410306), Victor Asua (5754053), Philip J. Rosenthal (47478), Stephen Tukwasibwe (5754050), Andrew Walakira (454001), Samuel L. Nsobya (5754047), Arthur Mpimbaza (51374)   +8 more
core   +1 more source

Hb SKMC and an unprecedented γδβ-thalassemia: first report from Iraq

Hematology
Background Thalassemias are genetic disorders of globin chain synthesis. In Iraq, β-thalassemia is more prevalent than α-thalassemia. This study identifies two unpredicted globin gene mutations, a rare α-globin gene mutation (Hb SKMC) and a novel γδβ ...
Rawand P. Shamoon, Amir Charkaneh, Elena Di Pierro, Milena Irrera, Cristina Curcio, Ahmed Yassin, Rozhgar A. Khailany   +6 more
doaj   +1 more source

Replication Data for: Blood Pressure and Arterial Stiffness in Kenyan Adolescents With α+Thalassemia

Background recent studies have discovered that a_globin is expressed in blood vessel walls where it plays a role in regulating vascular tone. We tested the hypothesis that blood pressure (BP) might differ between normal individuals and those with alpha ...
Etyang, A.O.
core   +1 more source

Restriction fragment length polymorphism in the interzeta hypervariable region for prenatal diagnosis of non-deletion α thalassemia

, 1988
A Bam Hi restriction fragment length polymorphism in the interzeta hypervariable region (IZ HR+) of the ζ-α gene cluster was used for the prenatal diagnosis of a pregnancy at risk for Hb H hydrops fetalis.
Todd, D, Chan, TK, Chan, TPT, Chan, V, Ghosh, A, Wong, ACK   +5 more
core   +1 more source

α-Thalassemia among pediatric Nb S homozygotes

, 1987
The number of α globin genes have been documented among 255 active SS patients under the age of 15 years. Ascertainment in the area served by our clinical program is 84%. The common -3.7 Kb α+ -Thalassemia (Th) had a gene frequency of 0.17. The incidence
McKie, Kathleen Mood, Kutlar, Abdullah, McKie, Virgil C., Felice, Alex, Zhao, J., Twenty-ninth Annual Meeting of the American Society of Hematology   +5 more
core  

Reactivation of the embryonic ζ-globin gene ameliorates severe forms of α-thalassemia. [PDF]

Nat Genet
Liu S, Ejaz A, King AJ, Olijnik AA, Sloane-Stanley J, Scott C, Amid A, Biggs D, Davies B, Eglinton J, Martyn G, Crossley M, Babbs C, Kassouf MT, Higgs DR.   +14 more
europepmc   +1 more source

Successful gene therapy for transfusion-dependent α-thalassemia: a case report. [PDF]

Blood Adv
Yin X, Qian L, Dong G, Chen Y, Zhou Y, Yang B, Liao G, Sun H, Guo H, Zeng X, Zou H, Ye T, He J, Yao W, Ouyang W, Zhang X, Liu C.   +16 more
europepmc   +1 more source