Results 81 to 90 of about 1,044,639 (194)

Effect of α⁺ Thalassemia on the Severity of Plasmodium falciparum Malaria in Different Sickle Cell Genotypes in Indian Adults: A Hospital-Based Study

, 2023
There is a paucity of literature on the association of α+-thalassemia, sickle-cell hemoglobin disorders, and malaria in India. This study aimed to understand the effect of α+-thalassemia on the severity of Plasmodium falciparum malaria in adults with ...
Kishalaya Das (15357398), Pradeep Kumar Mohanty (15357395), Siris Patel (6021758), Jogeswar Panigrahi (14225862), Prasanta Purohit (15357392)   +4 more
core   +1 more source

A rare −α27.6 deletion compounded with the hemoglobin constant spring mutation identified in a Chinese couple

Hematology
Background Thalassemia is a common hemoglobin disorder caused by genetic defects in a single autosomal gene. Based on the deficient globin strand, it can be classified as α-thalassemia or β-thalassemia.
Wei Li, Zhao-Yi Guo, Zi-Han Xiu, Min Long, Yan Xiao, Li-Yi Liu, Yu-Chen Chen, Si-Fan Zeng, Jing Zhang, Min Zhang   +9 more
doaj   +1 more source

AN OBSERVATIONAL STUDY OF THE EFFECT OF HEMOGLOBINOPATHY, ALPHA THALASSEMIA AND HEMOGLOBIN E ON P. VIVAX PARASITEMIA

Mediterranean Journal of Hematology and Infectious Diseases, 2018
Background: The protective effect of α-thalassemia, a common hematological disorder in Southeast Asia, against Plasmodium falciparum malaria has been well established.
Suparak Para, Puncharee Mungkalasut, Makamas Chanda, Issarang Nuchprayoon, Srivicha Krundsood, Chalisa Louicharoen Cheepsunthorn   +5 more
doaj   +1 more source

Differentiating β‐Thalassaemia From Iron Deficiency: Performance and Cut‐Off Dependency of More Than 40 Red Cell Discrimination Indices in a Large German Cohort

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Background Since the 1970s, more than 40 red blood cell–based formulas have been proposed to differentiate β‐thalassaemia trait (BTT) from iron deficiency (ID) and iron deficiency anaemia (IDA), the main causes of microcytic anaemia. In Germany, where haemoglobinopathies are rare in the autochthonous population but increasingly encountered due
Rafid Al‐Nabhan, Dani Hakimeh, Lena Oevermann   +2 more
wiley   +1 more source

Toileting Problems and Associated Factors in Adults Enrolled in the Global Angelman Syndrome Registry

Journal of Intellectual Disability Research, EarlyView.
ABSTRACT Background Angelman Syndrome (AS) is a rare neurodevelopmental disorder caused by the lack of expression of the UBE3A gene, which can result from abnormalities of the maternally inherited chromosome 15q11‐q13. The purpose of this study is to investigate the most common types of toileting problems in adults with AS and the associated factors of
Emma Walsh, Arlene Mannion, Sally Whelan, Evan Flynn, Megan Tones, Helen Heussler, Matthew Bellgard, Geraldine Leader   +7 more
wiley   +1 more source

Prevalence of Alpha(α)-Thalassemia in Southeast Asia (2010–2020): A Meta-Analysis Involving 83,674 Subjects [PDF]

, 2020
Alpha(α)-thalassemia is a blood disorder caused by many types of inheritable α-globin gene mutations which causes no-to-severe clinical symptoms, such as Hb Bart’s hydrops fetalis that leads to early foetal death. Therefore, the aim of this meta-analysis
Chong, Eric Tzyy Jiann, Lee, Ping Chin, Goh, Lucky Poh Wah, Lucky Poh Wah Goh, Eric Tzyy Jiann Chong, Ping-Chin Lee   +5 more
core   +1 more source

Evaluation of efficiencies of MCV, HbH inclusion body test and Gap-PCR in the screening of α-thalassemia: A case study of Lampang Hospital

Journal of Associated Medical Sciences, 2009
α-thalassemia is characterized by quantitive abnormality of α-globin chain commonly occur in Thailand. Heterozygote of α-thalassemia is clinically asymtomatic, but with modest alteration of hematologic parameters.
Tiemjan Kewkarnkha, Surasit Suwannasin, Thanusak Tatu   +2 more
doaj  

Off‐Label use of a lumen‐apposing metal stent for refractory pyloric stricture in a toddler

JPGN Reports, EarlyView.
Hamza Hassan Khan, Prateek Wali, Sumant Inamdar   +2 more
wiley   +1 more source

The prevalence of thalassemia in mainland China: evidence from epidemiological surveys

Scientific Reports, 2017
Comprehensive data regarding the epidemiology and prevalence of thalassemia in mainland China are lacking. To assess the prevalence of thalassemia, we performed a meta-analysis including 16 articles published from 1981 to 2015.
Ketong Lai, Guifeng Huang, Li Su, Yunyan He   +3 more
doaj   +1 more source

Knockdown of mitotically associated long non‐coding RNA dysregulates endothelial functions, transcriptome and proteome

The Journal of Physiology, EarlyView.
Abstract figure legend Downregulation of mitotically associated long non‐coding RNA (MANCR) disturbs transcriptome and proteome in endothelial cells, possibly leading to endothelial and vascular dysfunction in preeclampsia. Abstract Preeclampsia (PE) is a hypertensive disorder during pregnancy, which is characterized by a wide spectrum of endothelial ...
Si‐Yan Zhang, Chi Zhou, Jing Zheng
wiley   +1 more source