Results 81 to 90 of about 965,280 (210)
Diagnosis of α-thalassemia using droplet digital PCR [PDF]
, 2019 Most α-thalassemia occurs due to a large deletion in the α-globin gene. Common α-thalassemia with known mutations, such as Southeast Asian (SEA) type is readily diagnosed by Gap-PCR.
Mori, Kentaro +9 more
core
Diagram for the screening of hemoglobin variants, α/β-thalassemia and HPFH/δβ-thalassemia.
, 2013 Diagram for the screening of hemoglobin variants, α/β-thalassemia and HPFH/δβ-thalassemia.
Chun-Ping Lin (285488) +26 more
core +1 more source
British Journal of Haematology, EarlyView.Summary Cerebral macrovasculopathy (CV) is a major complication in children with sickle cell anaemia (SCA) and usually requires a long‐term transfusion programme (TP) to prevent stroke. This study aimed to identify factors predicting reversal of CV on TP in a single‐centre newborn cohort. Among 375 patients, 50 presented CV and received TP.
Julie Sommet +16 more
wiley +1 more source
HematologyBackground Thalassemia is a common hemoglobin disorder caused by genetic defects in a single autosomal gene. Based on the deficient globin strand, it can be classified as α-thalassemia or β-thalassemia.
Wei Li +9 more
doaj +1 more source
British Journal of Haematology, EarlyView.Summary In patients with sickle cell disease (SCD), parvovirus B19 infection (B19V) leads to acute anaemia (aplastic crisis), but may also be associated with other serious complications. We retrospectively analysed clinical data from paediatric SCD patients with B19V infections between 2023 and 2025, including symptoms, laboratory parameters ...
Matthias Bleeke +42 more
wiley +1 more source
Mediterranean Journal of Hematology and Infectious Diseases, 2018 Background: The protective effect of α-thalassemia, a common hematological disorder in Southeast Asia, against Plasmodium falciparum malaria has been well established.
Suparak Para +5 more
doaj +1 more source
Journal of the American Geriatrics Society, EarlyView.ABSTRACT Background Restrictive transfusion (Hb < 7 g/dL) is recommended for most perioperative patients, but the optimal threshold for those with cardiovascular disease or Hb 7–10 g/dL remains uncertain. The Perioperative Transfusion Trigger Score (POTTS), which integrates adrenaline requirement, FiO2, temperature, and angina history, may standardize ...
Shucong Liang +9 more
wiley +1 more source
Depression in mothers of children with thalassemia or blood malignancies: a study from Iran [PDF]
Background Several studies have found that parents of children with chronic diseases or disabilities have higher depression scores than control parents. Mothers usually take on the considerable part of the extra care and support that these children need
AliReza Farrokhi +9 more
core +1 more source
MOLECULAR ANALYSIS OF NON-TRANSFUSION DEPENDENT THALASSEMIA ASSOCIATED WITH HEMOGLOBIN E-β-THALASSEMIA DISEASE WITHOUT α--THALASSEMIA [PDF]
, 2019 Background: The finding of many Thai Hb E-β0-thalassemia patients with non-transfusion dependent thalassemia (NTDT) phenotype without co-inheritance of α-thalassemia has prompted us to investigate the existence of other genetic modifying factors ...
Kanokwan Sanchaisuriya +5 more
core +1 more source