Results 111 to 120 of about 3,503,326 (315)

Targeting α-synuclein as possible approach to combat Parkinson's disease

open access: yes, 2022
reservedLa malattia di Parkinson (PD) è una comune patologia neurodegenerativa caratterizzata da sintomi di tipo motorio e non motorio. I segni tipici di questo morbo sono la degenerazione dei neuroni dopaminergici a livello della substantia nigra pars ...
INCIARDI, ILENIA
core  

Διάχυτη Ενδοαγγειακή Πήξη: Παθοφυσιολογία, Διάγνωση, Αντιμετώπιση και η σχέση της με την κύηση και τον καρκίνο [PDF]

open access: yesEpistīmonika Chronika, 2018
Η διάχυτη ενδαγγειακή πήξη (ΔΕΠ) χαρακτηρίζεται από συστηματική ενεργοποίηση του μηχανισμού της πήξης με αποτέλεσμα την παραγωγή ινώδους και την δημιουργία θρόμβων σε διάφορα όργανα, με τελική κατάληξη την πολυοργανική ανεπάρκεια.
Α. Περδίου   +3 more
doaj  

Scientific Opinion on Flavouring Group Evaluation 212 Revision 3 (FGE.212Rev3): α,β‐unsaturated alicyclic ketones and precursors from chemical subgroup 2.6 of FGE.19

open access: yesEFSA Journal, 2015
The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to evaluate the genotoxic potential of 22 flavouring substances from subgroup 2.6 of FGE.19 in the Flavouring Group ...
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Σύγγραμμα περιοδικόν

open access: yes
Στον τόμο Α' περιλαμβάνονται 12 τεύχη σε 9 ...

core  

Phaedo, 69c: why are the βάκχοι the true philosophers?

open access: yesRevista Archai, 2015
a partir del análisis de Fedón, 69c se trata de dar respuesta a dos preguntas: 1) por qué sócrates cita un texto ór-fico, explicitando que tiene un sentido oculto (αἰνίττεσθαι), y 2) cómo llega a la conclusión de que los individuos a los que los órficos denominan βάκχοι son los verdaderos filósofos.
openaire   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

open access: yesFEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana   +3 more
wiley   +1 more source

Peroxidase-mediated cross-linking of bovine a-lactalbumin [PDF]

open access: yes, 2010
The research presented in this thesis aimed at controlling the horseradish peroxidase-catalyzed cross-linking of bovine α lactalbumin and the implications of this cross-linking for the foam stabilizing properties. Attention is also given to microreactors
Heijnis, W.H.
core  

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

open access: yesFEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés   +2 more
wiley   +1 more source

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