Results 111 to 120 of about 3,403,836 (312)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Περιοδικόν των μαθητών - Έτος Α' τευχ. 1-17 (1891-1892)
, 1892 Στο έτος Α' περιλαμβάνονται 17 ...
core
Revista ArchaiIn this paper, I aim to reject the thesis that ancient democracy, according to Aristotle, is defined by majority rule for its own benefit. I advocate for an alternative thesis, (which easily incorporates what is true in the rejected view), namely, that it is the concept of eleutheria, particularly as understood in Politics VI.2 and VI.9, that holds ...
openaire +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
, 2013 Η εργασία αυτή πραγματεύεται την σκέψη του Charles Taylor πάνω στη νεωτερικότητα, τις τρεις δυσανεξίες που εντοπίζει σε αυτή και την συνακόλουθη θεωρία του που αποτελεί συνάμα και μία πρόταση ώστε να τις ξεπεράσουμε.
Ζάρρας, Ιωάννης Α
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Crystal structure of N-phenyldichloroacetamide, C8H7NOCl2
Zeitschrift für Kristallographie - New Crystal Structures, 1998 Pal Α. K. +2 more
doaj +1 more source