Results 91 to 100 of about 3,403,836 (312)
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Drug Design, Development and Therapy, 2019 Laiba Arshad,1 Ibrahim Jantan,2 Syed Nasir Abbas Bukhari31Department of Pharmacy, Forman Christian College (A Chartered University), Lahore, Pakistan; 2School of Pharmacy, Faculty of Health and Medical Sciences, Taylor’s University, Subang Jaya ...
Arshad L, Jantan I, Bukhari SNA
doaj
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Οικογενειακόν και φιλολογικόν περιοδικόν
, 1891 Στο Έτος Β' - Περίοδος Β' - Τόμος Α' περιλαμβάνονται 8 τεύχη σε 7 ...
core
Comparative diversity of aquatic plants in three Central European regions
Frontiers in Plant ScienceFreshwaters are among the most threatened ecosystems globally, with biodiversity declining at far greater rates than the biodiversity of the most affected terrestrial ecosystems.
Marek Svitok +10 more
doaj +1 more source
EFSA Journal, 2015 The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to evaluate the genotoxic potential of 10 flavouring substances from FGE.19 subgroup 4.4, in the Flavouring Group Evaluation
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Comparison of feeding indices and digestive enzymes of pomegranate neckworm, Ectomyelois ceratoniae (Lep.: Pyralidae) on three pomegranate cultivars [PDF]
نامه انجمن حشرهشناسی ایران, 2013 In this research nutritional indices of pomegranate neckworm on the three cultivars of pomegranate including Malas-Daneh-Sia, Gabri and Shahvar were studied under controlled conditions (30 ± 1ºC, 70 ± 5% RH and 16L: 8D).
D. Zare +3 more
doaj
EFSA Journal, 2015 The EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids was requested to evaluate the genotoxic potential of flavouring substances from subgroup 2.2 of FGE.19 in the Flavouring Group Evaluation 208 Revision 1 (FGE.208Rev1). The
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)
doaj +1 more source