Results 81 to 90 of about 3,503,326 (315)

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Designing methodology of science support in decision making for the protection of historical buildings and monuments with sustainability parameters of materials

open access: yes, 2011
86 σ.Σχεδιασμός μεθοδολογίας λήψης απόφασης για την προστασία των ιστορικών κτιρίων και των μνημείων με κριτήρια αειφορίας των υλικώνDesign of methodology in decision making for the protection of historical buildings and monuments with sustainability ...
Athanasiadis, Vasileios A.   +1 more
core   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Περιοδικόν των μαθητών - Έτος Α' τευχ. 1-17 (1891-1892)

open access: yes, 1892
Στο έτος Α' περιλαμβάνονται 17 ...

core  

Alpha adrenergic receptors are involved in the contractile activity of neuropeptide Y in the porcine isolated ovarian artery

open access: yesVeterinární Medicína, 2003
The objective of this study was to determine whether α-adrenergic receptors are involved in the contractile activity of neuropeptide Y (NPY) in the porcine isolated ovarian artery collected from immature pigs and from the animals on day 1-5, 8-13 and 17 ...
W. Markiewicz
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Επιθεώρησις της Ανατολής - Έτος Α' (1921-1922)

open access: yes, 1921
Στο Έτος Α’ περιλαμβάνονται 3 ...

core  

Designing and Creating a Synthetic Omega Oxidation Pathway in Saccharomyces cerevisiae Enables Production of Medium-Chain α, ω-Dicarboxylic Acids

open access: yesFrontiers in Microbiology, 2017
Medium-chain (C8–C14) α, ω-dicarboxylic acids (α, ω-DCAs), which have numerous applications as raw materials for producing various commodities and polymers in chemical industry, are mainly produced from chemical or microbial conversion of petroleum ...
Li Han   +6 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Diagnostic approach and gene analysis of the α+-thalassaemia in the Cretan population

open access: yes, 2007
Μελετήσαμε με DNA ανάλυση 58 πιθανούς α+-θαλασσαιμικούς φορείς οι οποίοι επελέγησαν με κριτήρια α) την παρουσία ήπιων μορφολογικών ερυθροκυτταρικών αλλοιώσεων, β) τις φυσιολογικές ή ελαφρά μειωμένες τιμές ερυθροκυτταρικών δεικτών MCV και MCH, γ) τα ...
Ρεπαπίνου, Ζωή   +1 more
core  

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