Results 101 to 110 of about 3,147,935 (268)

Comparison of feeding indices and digestive enzymes of pomegranate neckworm, Ectomyelois ceratoniae (Lep.: Pyralidae) on three pomegranate cultivars [PDF]

نامه انجمن حشره‌شناسی ایران, 2013
In this research nutritional indices of pomegranate neckworm on the three cultivars of pomegranate including Malas-Daneh-Sia, Gabri and Shahvar were studied under controlled conditions (30 ± 1ºC, 70 ± 5% RH and 16L: 8D).
D. Zare, J. Jalali Sendi, A. Zibaee, A. Jafary Nodoushan   +3 more
doaj  

Scientific Opinion on Flavouring Group Evaluation 208 Revision 1 (FGE.208Rev1): Consideration of genotoxicity data on representatives for 10 alicyclic aldehydes with the α,β‐unsaturation in ring / side‐chain and precursors from chemical subgroup 2.2 of FGE.19

EFSA Journal, 2015
The EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids was requested to evaluate the genotoxic potential of flavouring substances from subgroup 2.2 of FGE.19 in the Flavouring Group Evaluation 208 Revision 1 (FGE.208Rev1). The
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Scientific Opinion on Flavouring Group Evaluation 212 Revision 3 (FGE.212Rev3): α,β‐unsaturated alicyclic ketones and precursors from chemical subgroup 2.6 of FGE.19

EFSA Journal, 2015
The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to evaluate the genotoxic potential of 22 flavouring substances from subgroup 2.6 of FGE.19 in the Flavouring Group ...
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Sintesis α-Fe2O3 menggunakan metode sol gel

, 2013
In this reseach was succeeded make powder α-Fe2O3 with particle size 202.64 nm. Synthesis using Sol-Gel method with SiO2 coating derived from Si(OC2H5)4 at temperature of 750 oC for 5 hours.
Purnomo, Pandu
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Diagnostic approach and gene analysis of the α+-thalassaemia in the Cretan population

, 2007
Μελετήσαμε με DNA ανάλυση 58 πιθανούς α+-θαλασσαιμικούς φορείς οι οποίοι επελέγησαν με κριτήρια α) την παρουσία ήπιων μορφολογικών ερυθροκυτταρικών αλλοιώσεων, β) τις φυσιολογικές ή ελαφρά μειωμένες τιμές ερυθροκυτταρικών δεικτών MCV και MCH, γ) τα ...
Ρεπαπίνου, Ζωή, Repapinou, Zoi   +1 more
core  

Targeting α-synuclein as possible approach to combat Parkinson's disease

, 2022
reservedLa malattia di Parkinson (PD) è una comune patologia neurodegenerativa caratterizzata da sintomi di tipo motorio e non motorio. I segni tipici di questo morbo sono la degenerazione dei neuroni dopaminergici a livello della substantia nigra pars ...
INCIARDI, ILENIA
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source