Results 141 to 150 of about 3,403,836 (312)
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
High prevalence of autoantibodies neutralizing type I IFNs in Japanese patients with hepatitis C. [PDF]
Taniguchi M +20 more
europepmc +1 more source
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Εισαγωγή - εμπορικαί πράξεις - έμποροι - εμπορικαί επιχειρήσεις
Η χρονιά έκδοσης δεν αναφέρεται στο τεκμήριο. Εισάγεται κατά προσέγγιση.2026 ΚΟΥΤΑ
Σπηλιόπουλος, Κυριάκος Β.
core +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
When Pathologies Collide: The Intersection of Tau and Alpha-Synuclein in Neurodegenerative Diseases. [PDF]
Hunt JN, Kortagere S.
europepmc +1 more source
Using a dataset corresponding to 9 fb(-1) of integrated luminosity collected with the LHCb detector between 2011 and 2018 in proton-proton collisions, the decay-time distributions of the decay modes B-s(0) -> J/psi eta' and B-s(0) -> J/psi pi(+) pi(-) are studied.
Aaij, R. +5 more
openaire +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Zero-Inflated Promotion Cure-Rate Models With Frailty and Flexible Activation Schemes. [PDF]
Assunção D +5 more
europepmc +1 more source

