Results 161 to 170 of about 3,503,326 (315)

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Preventive Immunomodulatory Effects of Doxycycline and Hyperbaric Oxygen Therapy on Serum Tumor Necrosis Factor-<i>α</i> and Interleukin-6 Levels in a Rat Model of Malaria. [PDF]

J Parasitol Res
Risma R, Kurniawan IMP, Pratiknya DE, Marietta ET, Martua ET, Nathania J.   +5 more
europepmc   +1 more source

A measurement of ΔΓs

Using a dataset corresponding to 9 fb(-1) of integrated luminosity collected with the LHCb detector between 2011 and 2018 in proton-proton collisions, the decay-time distributions of the decay modes B-s(0) -> J/psi eta' and B-s(0) -> J/psi pi(+) pi(-) are studied.
Aaij, R., Adlarson, Patrik, Eklund, Lars, Kupsc, Andrzej, Ruiz Vidal, J., Zunica, G.   +5 more
openaire   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Molecular Mimicry Inference, Therapeutic Target Identification, and Natural Product Inhibition Study in Cardiobacterium valvarum through Bioinformatics Approach

ACS Omega
Calvin R. Wei, Zarrin Basharat, Godwin C. Lang’at   +2 more
doaj   +1 more source

Emerging Evidence Suggests That N-Glycosylation Pathway Perturbation Has a Greater Impact than Microbial Depletion on α-Gal Antigen Biogenesis in Lone Star Tick (<i>Amblyomma americanum</i>) Salivary Glands. [PDF]

Microorganisms
Sharma SR, Karim S.
europepmc   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Cerebrospinal fluid and dural accumulation of α-synuclein impairs CNS clearance in Parkinson's disease. [PDF]

J Exp Med
Stevenson TJ, Vinnell L, McCullough SJC, Flyger DX, Highet B, Wiseman JA, Watkin B, Hitpass Romero K, Low VF, Smith AM, Wu A, Fong DM, Grimsey NL, Dieriks BV, Turner CP, Young D, Curtis MA, Faull RLM, Dragunow M, Rustenhoven J.   +19 more
europepmc   +1 more source

Almost α-γ-Irresolute Functions

Journal of New Results in Science, 2014
functions called almost γ-irresolute functions and almost α-γirresolute functions in topological spaces. We obtain several characterizations of these classes and study their properties and investigate the relationships with the known non-continuous ...
openaire   +2 more sources

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source