Results 151 to 160 of about 3,147,935 (268)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Immunohistochemical localization of tumor necrosis factor-α in gastrointestinal tissues of budgerigars naturally infected with Macrorhabdus ornithogaster. [PDF]

Vet Res Commun
Atay D, Ozmen O.
europepmc   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Synaptic vesicle architecture modulates α-synuclein conformation and pathogenic transitions in Parkinson's disease. [PDF]

Biosci Rep
Ranjan P.
europepmc   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Limitted Degradation of α-actinin in the Ordinary Muscle of Cultured Red Sea Bream during Storage in Ice

, 2001
養殖マダイ普通筋α-アクチニン抗体を作成し, これを用いて養殖マダイ氷蔵中における普通筋中α-アクチニンの分解をSDS-PAGEとイムノブロッティングで解析した。作成したα-アクチニン抗体はマダイ普通筋中のα-アクチニンのみならず, そのパパイン分解物とも反応性を示した。本抗体は免疫電顕による観察で, 筋原線維のZ線に特異的に反応し, 他の細胞内小器官等には反応を認めなかった。普通筋中α-アクチニンは氷蔵1日目から自己消化され, 5日目以降ではすべて分子量90kDa&acd ...
槌本, 六良, 橘, 勝康, 三嶋, 敏雄, 原, 研治, 鈴木, 秀一, 八木, 基明   +5 more
core  

Molecular Basis for the Divergent Inhibition of α-Amylase and α-Glucosidase by Phenolic Acids: The Critical Role of Hydroxyl Substitution. [PDF]

Foods
Yang S, Li Y, Han W, Cao W, Hu Z, Zhu Z, Li M, Feng J, Zhang J.   +8 more
europepmc   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Implications of a local overproduction of tumor necrosis factor-α in complex regional pain syndrome

, 2011
Objective. To review the implications of a local overproduction of tumor necrosis factor-α for the pathogenesis and treatment of complex regional pain syndrome. Background.
Walker, S., Drummond, P.D.
core  

Crystal structure of N-methyl-N-phenyl-(2-methyl-3-phenylcyclopropenylidene) ammonium Perchlorate, C17H16N+^CIO4- and of 3-cyano-1,2,3- triphenylcycloprop-1-ene-benzene (1/2), C22H15N · 2СбНб

Zeitschrift für Kristallographie - New Crystal Structures, 1998
Imgartinger H., Altreuther Α., Krebs Α., Toda F.   +3 more
doaj   +1 more source