Results 151 to 160 of about 6,855,939 (294)

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Nanoencapsulated α-Mangostin Loaded Chitosan-Alginate Hydrogel Films for Enhanced Topical Anti Acne Therapy. [PDF]

Drug Des Devel Ther
Yuniarsih N, Chaerunisaa AY, Mohammed AFA, Elamin KM, Muchtaridi M, Wathoni N.   +5 more
europepmc   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Correction: α-Synuclein modulates tau spreading in mouse brains. [PDF]

J Exp Med
Bassil F, Meymand ES, Brown HJ, Xu H, Cox TO, Pattabhiraman S, Maghames CM, Wu Q, Zhang B, Trojanowski JQ, Lee VM.   +10 more
europepmc   +1 more source

Βιβλιοκρισίαι: A. Orabar, L’ empereur dans Vart byzantin. Recherches sur l’art officiel de l’Empire d’Orient. Paris, 1936. Les Belles Lettres. (Publications de la Faculte des Lettres de l’ Universite de Strasbourg, Fascicule 75). 296 σελίδες μετά 12 εικόνων εν τω κειμένω και 40 πινάκων εν τέλει [PDF]

, 1936
Ξυγγόπουλος, Α.
core  

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Chiral manganese halide isomers: decoding the spatial stacking effect on second-harmonic generation circular dichroism. [PDF]

Chem Sci
Li J, Wei J, Luo Q, Pang W, Liu H, Chen P, Zhou L, Zhang JZ, Luo B, Pang Q.   +9 more
europepmc   +1 more source

Βιβλιοκρισίαι: G. de Jerphanion. La voix des monuments. Etudes d' archeologie. Nouvelle serie, Roma-Paris, 1938. (Pontificio Institute Orientate Les Editions d' Art et d'Histoire). 332 σελίδες μετά 23 εικόνων και 48 φωτοτ. Πινάκων [PDF]

, 1938
Ξυγγόπουλος, Α.
core  

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

An updated view on lagging strand DNA replication: implications for the replication stress response. [PDF]

Cell Cycle
Martín-Rufo R, Lecona E.
europepmc   +1 more source