Results 171 to 180 of about 6,855,939 (294)

Sex-Dependent Dynamics of Behavioural and Neuropathological Changes in an A53T Alpha-Synuclein Mouse Model of Parkinson's Disease. [PDF]

Cell Mol Neurobiol
Zubelzu M, Bidgood R, Murueta-Goyena A, Ruiz-Ortega JÁ, Lafuente JV, Morera-Herreras T.   +5 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Direct current stimulation induced reduction in α-synuclein in primary neurons: targeting Parkinson's disease. [PDF]

Brain Commun
Bechkos S, Ryan SD, Ross A, Sun H, Hayley S.   +4 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Key considerations for measuring α-galactosidase A activity after long-term migalastat therapy-Avoiding in vitro inhibition effects. [PDF]

Mol Genet Metab Rep
Munakata M, Iwamoto T, Chen W, Akiyama K, Eto Y.   +4 more
europepmc   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Optical response and electron energy loss spectra of boron arsenide using linear response theory. [PDF]

RSC Adv
Joshi N, Jangir S, Joshi KB.
europepmc   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Flexible Morphology-Controlled Preparation of α‑Calcium Sulfate Hemihydrate from FGD Gypsum in Ethylene Glycol Water Solutions. [PDF]

ACS Omega
Gao X, Wang Z, Yang X, Wang Y, Yu J, Cheng F, Wu L, Zhang P, Zeng Y, Fu H.   +9 more
europepmc   +1 more source

Βιβλιοκρισίαι: Georgios Phrantzes, Chronicon. Vol. I edidit I. B. Papadopoulos. Lipsiae, B. G. Teubner, 1935. Σελ. XXXIV-201. (Bibliotheca Teubneriana 1954). I. B. Papadopoulos, Phrantzes est-il reellment l’auteur de la grande chronique quiporte son nom? Extrait des Actes du IV Congres International des etudes byzantines. (Bulletin de I’Institut archeologipue bulgare, tome IX, Sofia 1935, οελ. 177 -189) [PDF]

, 1936
Σιγάλας, Α.
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