Results 41 to 50 of about 3,147,935 (268)

Co-administration of vitamin E and selenium in vivo and in vitro ameliorates the toxic effects caused by ivermection and doramectin

Veterinární Medicína, 2020
Avermectins are used in animals and humans for their broad-spectrum effects against parasites causing cytotoxicity and damage to the cellular DNA. In this study, we examined the toxicological changes of ivermectin (IVM) and doramectin (DME) with or ...
Ahmed Ezzat Ahmed, Mohammed A. Al-Kahtani, Atef M. Khalil, Ali S. Alshehri, Ashraf A. Elghoneimy, Serag Eldin I. Elbehairi, Mohammad Y. Alfaifi, Ali A. Shati, Kareem S. Morsy, Mohammed A. Alshehri, Haitham I. El-Mekkawy, Ahmed A. Elmansi   +11 more
doaj   +1 more source

Effects of the Fluid Replacement Method During Online Hemodiafiltration on the Solute Removal Performance and Biocompatibility Using the Asymmetric Cellulose Triacetate Membrane

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Pre‐dilution online hemodiafiltration (Pre‐HDF) is predominantly used in Japan, whereas post‐dilution online HDF (Post‐HDF) is more common in Europe. An asymmetric cellulose triacetate (ATA) membrane may improve biocompatibility.
Kenji Sakurai, Yoshitaka Kurihara, Fumi Yamauchi, Hiromi Hosoya, Takeshi Saito   +4 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Overexpression of Endometrial Estrogen Receptor-Alpha in The Window of Implantation in Women with Unexplained Infertility [PDF]

International Journal of Fertility and Sterility, 2018
Background Failure in the endometrial receptivity may account for a significant number of infertility cases including unexplained infertility in women.
Mehran Dorostghoal, Hamid-o-allah Ghaffari, Farideh Moramezi, Narjes Keikhah   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Are Therapies That Target α-Synuclein Effective at Halting Parkinson’s Disease Progression? A Systematic Review

, 2023
There are currently no pharmacological treatments available that completely halt or reverse the progression of Parkinson’s Disease (PD). Hence, there is an unmet need for neuroprotective therapies.
Wayne G. Carter, Maryam ALNasser, Carter, Wayne G., Abbie T. Rodger, ALNasser, Maryam, Rodger, Abbie T.   +5 more
core   +1 more source

Συμβολή στη μνημειακή τοπογραφία της αρχαίας πόλης της Χίου [PDF]

, 2020
Σημείωση: διατίθεται συμπληρωματικό υλικό σε ξεχωριστό ...
Τσαρδάκα, Δέσπονα Α.
core   +1 more source

The synergistic effect of daidzein and α-tocopherol or ascorbic acid on microsome and LDL oxidation

Czech Journal of Food Sciences, 2010
Isoflavone daidzein brings potential health benefits. Its antioxidant properties are considered to be responsible in part for its protective effects.
Heya Wang, Masibo Wanyonyi Martin, Shian Yin   +2 more
doaj   +1 more source