Results 31 to 40 of about 3,403,836 (312)
Thermodynamics-based bounding surface model for overconsolidated clay
Based on the framework of thermodynamics and critical state soil mechanics, a new α-β yield surface is formulated in the triaxial space. Based on the non-associated flow rule and bounding surface framework, the proposed model can simulate the correct ...
CHEN Yan-ni , YANG Zhong-xuan
doaj +1 more source
ABSTRACT Background Children with sickle cell anemia (SCA) in low‐income settings are at risk of severe malnutrition, but optimal nutritional management has not been established. We evaluated an intensified ready‐to‐use therapeutic food (RUTF) regimen in children with persistent severe malnutrition after initial treatment and assessed whether early ...
Safiya Gambo +9 more
wiley +1 more source
Avermectins are used in animals and humans for their broad-spectrum effects against parasites causing cytotoxicity and damage to the cellular DNA. In this study, we examined the toxicological changes of ivermectin (IVM) and doramectin (DME) with or ...
Ahmed Ezzat Ahmed +11 more
doaj +1 more source
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida +6 more
wiley +1 more source
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
α-Tocopherol in plasma and milk from organically managed dairy cows fed natural or synthetic vitamin E or seaweed [PDF]
The objective was to compare the effects of supplementing lactating dairy cows with synthetic (All-rac), natural (RRR) α-tocopheryl acetate or seaweed with a control on the concentration of α-tocopherol in blood and milk.
Steinshamn, Håvard +3 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Are Therapies That Target α-Synuclein Effective at Halting Parkinson’s Disease Progression? A Systematic Review [PDF]
There are currently no pharmacological treatments available that completely halt or reverse the progression of Parkinson’s Disease (PD). Hence, there is an unmet need for neuroprotective therapies.
Wayne G. Carter +5 more
core +1 more source
Overexpression of Endometrial Estrogen Receptor-Alpha in The Window of Implantation in Women with Unexplained Infertility [PDF]
Background Failure in the endometrial receptivity may account for a significant number of infertility cases including unexplained infertility in women.
Mehran Dorostghoal +3 more
doaj +1 more source

