Results 101 to 110 of about 1,291,117 (154)

Serum autoantibodies against α7-nicotinic receptors in subgroups of patients with bipolar disorder or schizophrenia: clinical features and link with peripheral inflammation

Translational Psychiatry
There is growing evidence that autoantibodies (AAbs) against proteins expressed in the brain are playing an important role in neurological and psychiatric disorders.
Estelle Darrau, Elise Jacquemet, Stéphanie Pons, Laurène Schlick, Marios Zouridakis, Ching-Lien Wu, Jean-Romain Richard, Caroline Barau, Philippe Le Corvoisier, Robert Yolken, Ryad Tamouza, Marion Leboyer, Uwe Maskos   +12 more
doaj   +1 more source

Pesticide exposure during pregnancy, like nicotine, affects the brainstem α7 nicotinic acetylcholine receptor expression, increasing the risk of sudden unexplained perinatal death

, 2015
This study indicates the impact of nicotine and pesticides (organochlorine and organophosphate insecticides used in agriculture) on neuronal α7-nicotinic acetylcholine receptor expression in brainstem regions receiving cholinergic projections in human ...
Corna, Melissa Felicita, CAPPIELLO, ACHILLE, Pusiol, Teresa, Lavezzi, Anna Maria, TERMOPOLI, VERONICA, Matturri, Luigi   +5 more
core   +2 more sources

Proteomic Analysis of an α7 Nicotinic Acetylcholine Receptor Interactome

, 2016
The α7 nicotinic acetylcholine receptor (nAChR) is well established as the principal high-affinity α-bungarotoxin-binding protein in the mammalian brain.
William J. Brucker (2382634), Joao A. Paulo (397190), Edward Hawrot (781725)   +2 more
core   +1 more source

Effects of mutations of a glutamine residue in loop D of the α7 nicotinic acetylcholine receptor on agonist profiles for neonicotinoid insecticides and related ligands

, 2002
1. Neonicotinoid insecticides are agonists of insect nicotinic acetylcholine receptors (AChRs) and show selective toxicity for insects over vertebrates.
Matsuda, Kazuhiko, Komai, Koichiro, Masaru Shimomura, Koichiro Komai, Miki Akamatsu, Sattelle, David B., Kazuhiko Matsuda, Shimomura, Masaru, Okuda, Hiroshi, David B Sattelle, Akamatsu, Miki, Hiroshi Okuda   +11 more
core   +1 more source

α7-Nicotinic receptor agonist

α7-Nicotinic receptor agonist regulating NLRP3 inflammasome ...
Sanaullah Sajid (18331881)
core   +1 more source

Nucleic acids encoding functional splice variants of the α7 nicotinic acetylcholine receptor subunit and methods for producing the encoded proteins [PDF]

, 2009
The present invention concerns a novel α7 nicotinic receptor subunit isoform, α7-2. The α7-2 isoform contributes to novel acetylcholine receptors (AChRs) with pharmacological and biophysical properties distinct from those of wild ...
Severance, Emily, Cuevas, Javier
core  

Structural basis for allosteric agonism of human α7 nicotinic acetylcholine receptors

Cell Discovery
The α7 nicotinic acetylcholine receptor (nAChR), a pentameric ligand-gated ion channel, plays important roles in cognition, neuroprotection, and anti-inflammation.
Sanling Liu, Yining Zheng, Haopeng Chen, Xin Li, Qipeng Yan, Wenjun Mu, Yaning Fu, Huan Chen, Hongwei Hou, Lei Liu, Changlin Tian   +10 more
doaj   +1 more source

Adult-onset hippocampal α7 nicotinic acetylcholine receptor loss rapidly drives Alzheimer-like neuropathology in mice. [PDF]

Front Pharmacol
Li J, Liu G, Wang X, Song Z, Chen H, Hou H, Hu Q.   +6 more
europepmc   +1 more source

Electroacupuncture Attenuates Cerebral Ischemia-Reperfusion Injury via Vagus Nerve-α7 Nicotinic Acetylcholine Receptor-Dependent Microglial Polarization. [PDF]

J Am Heart Assoc
Niu JY, Luo X, Li XD, Zhang J, Wu Q, Pei YF, Wang JQ, Zhao QK, Wang Y, Zhang G, Chen HS.   +10 more
europepmc   +1 more source

Pan-cancer expression, methylation, and prognostic significance of α7 nicotinic acetylcholine receptor in tumor immunology. [PDF]

Biochem Biophys Rep
Bai X, Ma T, Shi L, Wang P, Zhao D, Long J, Hai Y, You Y, Zhao R, Ma L.   +9 more
europepmc   +1 more source