Organocatalytic Michael addition–lactonisation of carboxylic acids using α,β-unsaturated trichloromethyl ketones as α,β-unsaturated ester equivalents [PDF]
, 2014 The authors thank the Royal Society for a University Research Fellowship (ADS), The Carnegie Trust for the Universities of Scotland (LCM), Syngenta/EPSRC (Case award to DGS), GSK/EPSRC (CASE award to SRS), the EU (IEF for CS), and the European Research ...
Morrill, L.C. +19 more
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, 2016 The aldol reaction of methyl ketones and α,β-unsaturated trifluoromethyl ketones occurred under mild conditions with the combination of proline-derived N-sulfonylamide and trifluoroacetic acid as the catalyst to give the corresponding unsaturated α ...
Yan Zhao (58882) +2 more
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Insights into the Mechanism and Regioselectivity of Palladium-Catalyzed Arylation of α,β-Unsaturated Ketones [PDF]
, 2023 Transition-metal catalyzed coupling reactions of carbonyl compounds using simple chemical feedstocks have become a cornerstone of modern synthetic organic chemistry.
Xiaoxi, Su +3 more
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A Mild Isomerization Reaction for β,γ-Unsaturated Ketone to α,β-Unsaturated Ketone
, 2013 A series of β,γ-unsaturated ketones were isomerized to their corresponding α,β-unsaturated ketones by the introduction of DABCO in iPrOH at room temperature. The endo-cyclic double bond (β,γ-position) on ketone was rearranged to exo-cyclic double bond (α,
李世元; Lee, Adam Shih-yuan; 林美君; Lin, Mei-chun; Wang, Shu-huei; 王淑惠; Lin, Li-shin;林立信
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, 2014 A series of β-bromoketones and β-chloroketones were synthesized by the addition reactions of α,β-unsaturated ketones under BX3 (X = Br, Cl) and ethylene glycol reaction system.
Lee, Adam Shih-Yuan; Wang, Shu-Huei; Chang, Yu-Ting
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)‐β‐Nitroenones into β‐Nitro‐β,γ‐Unsaturated Ketones under Microwave Conditions
, 2020 We report herein an unprecedented conversion of β-nitroenones into β-nitro-β,γ-unsaturated ketones. The reaction proceeds under microwave irradiation, furnishing products in good yields and excellent diastereoselectivity.
Palmieri A. +17 more
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Regioselective synthesis of β-fluoro-α,β-unsaturated ketones by the reaction of β-diketones with DFMBA [PDF]
, 2009 The deoxyfluorination reaction of β-diketones with N,N-diethyl-α,α-difluoro-m-methylbenzylamine (DFMBA) gave β-fluoro-α,β-unsaturated ketones in good yields.
Sano, Keisuke +2 more
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β′-Hydroxy-α,β-unsaturated ketones: A new pharmacophore for the design of anticancer drugs
, 2006 A series of β′-hydroxy-α,β-unsaturated ketones were prepared by means of an iron(III) catalyzed domino process. The in vitro antiproliferative activities were examined in the human solid tumor cell lines A2780, SW1573, and WiDr. The results showed that β′
Padrón, Juan I. +7 more
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Isothiourea-mediated one-pot synthesis of trifluoromethyl substituted 2-pyrones [PDF]
, 2014 The authors thank the Royal Society for a University Research Fellowship (ADS) and the EPSRC (EP/J018139/1, DSBD) for funding.A one-pot isothiourea-mediated Michael addition/lactonization/thiol elimination cascade sequence for the formation of 4,6 ...
Smith, Andrew D. +9 more
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γ,δ-Unsaturated β-Diketones by Acylation of Ketones
, 2016 γ,δ-Unsaturated β-diketones have been prepared by the acylation of ketones with N-acylbenzotriazoles of various aliphatic and aromatic α,β-unsaturated carboxylic ...
Sandeep K. Singh (1849165) +2 more
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