Safety of 27 flavouring compounds providing a milky-vanilla flavour and belonging to different chemical groups for use as feed additives in all animal species (FEFANA asbl) [PDF]
, 2023 Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety of 27 compounds to provide a milky-vanilla flavour belonging to different chemical groups, when used as sensory additives in feed for all ...
Anguita M. +24 more
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Photochemical Approaches to Complex Chemotypes: Applications in Natural Product Synthesis. [PDF]
, 2016 The use of photochemical transformations is a powerful strategy that allows for the formation of a high degree of molecular complexity from relatively simple building blocks in a single step. A central feature of all light-promoted transformations is the
Kärkäs, Markus D. +2 more
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A Dive Into Forty Years of Research on Organic Superbases: From Design to Applications
Journal of Computational Chemistry, Volume 46, Issue 28, October 30, 2025.This review covers the design and application of various neutral organic superbases with carbon, nitrogen, boron, silicon and germanium centers as basic sites. Their utility as organocatalysts has been reported with particular attention given to applications of commercially accessible organic superbases in some pivotal reactions.
Rabindranath Lo, Bishwajit Ganguly
wiley +1 more source
A one-pot and eco-friendly synthesis of novel β-substituted-α-halomethyl acrylates and the bioactivity of these compounds in an in vitro model of mast cell degranulation induced by pro-inflammatory stimuli [PDF]
, 2023 The goal of the present work was to develop novel β-substituted-α-halomethyl acrylates from a methodology in an aqueous phase and to evaluate their bioactivity as potential inhibitors of mast cell activation.
Ceñal, Juan Pedro José +4 more
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ChemCatChem, Volume 17, Issue 18, September 19, 2025.This review elucidates structure‐activity relationships in Ru‐supported catalysts for hydrodeoxygenation of lignin‐derived phenolics to cyclohexane‐based products. It highlights the synergy between Ru nanoparticle size, dispersion, and electronic state with tailored support acidity and defects, enabling efficient hydrogenation–deoxygenation.
Gousia Begum +4 more
wiley +1 more source
EFSA Journal, Volume 23, Issue 7, July 2025.Abstract Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of a tincture from the leaves or aerial parts of Mentha × piperita L. (peppermint tincture) when used as a sensory additive in feed and in water for drinking for all animal species. The product is a ■■■■■ solution, with a
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) +23 more
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Analysis of the Cramer classification scheme for oral systemic toxicity - implications for its implementation in Toxtree [PDF]
, 2011 In the application of the Threshold of Toxicological Concern (TTC) concept to non-cancer endpoints, the decision tree proposed by Cramer, Ford and Hall in 1978, commonly referred to as the Cramer scheme, is probably the most widely used approach for ...
LAPENNA SILVIA, WORTH Andrew
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Recent Advances in the α‐Hydrazination (α‐Amination) of Carbonyl Compounds
European Journal of Organic Chemistry, Volume 28, Issue 17, May 21, 2025.In recent years, notable progress has been achieved in the α‐hydrazination (α‐amination) of carbonyl compounds, especially in the direct asymmetric electrophilic α‐hydrazination with dialkyl azodicarboxylates. This review summarizes all the methods that appeared over the past decade, categorized based on the type of the reactive chiral intermediate ...
Dina Scarpi +2 more
wiley +1 more source
Pioneering Metal‐Free Late‐Stage C−H Functionalization Using Acridinium Salt Photocatalysis
Chemistry – A European Journal, Volume 30, Issue 67, December 2, 2024.Organic dyes are powerful photocatalysts in organic transformations due to their availability, adaptable absorption, and diverse structures. Acridinium‐based organo‐photocatalysts, notable for visible light responsiveness, efficiently functionalize inert C−H bonds under mild conditions without transition metals.
Shyamal Kanti Bera, Andrea Porcheddu
wiley +1 more source
Syntheses of Isoxazoline-Based Amino Acids by Cycloaddition of Nitrile Oxides and Their Conversion into Highly Functionalized Bioactive Amino Acid Derivatives [PDF]
, 2012 The present account illustrates the syntheses of isoxazoline- based amino acids by the cycloaddition of 1,3-dipolar nitrile oxides to the C–C double bond of unsaturated amino acid derivatives, with focus on the regio- and stereoselectivities of the ...
Fülöp, Ferenc +2 more
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