Results 11 to 20 of about 69,375 (242)

Catalytic Enantioselective Methods for Synthesis of 1,2-Amino Tertiary Alcohols and Their Analogues. [PDF]

Chem Rev
Malcolmson SJ, Rahim F.
europepmc   +2 more sources

Iridium-catalyzed enantioselective synthesis of chiral γ-amino alcohols and intermediates of (S)-duloxetine, (R)-fluoxetine, and (R)-atomoxetine

Communications Chemistry, 2022
Enantioselective hydrogenation of β-amino ketones is a powerful tool to produce bioactive molecules, but their asymmetric transformation is synthetically challenging.
Chengyu Liu, Lei Zhang, Liming Cao, Yan Xiong, Yueyue Ma, Ruihua Cheng, Jinxing Ye   +6 more
doaj   +1 more source

The Trypanosoma cruzi enzyme TcGPXI is a glycosomal peroxidase and can be linked to trypanothione reduction by glutathione or tryparedoxin. [PDF]

, 2002
Trypanosoma cruzi glutathione-dependent peroxidase I (TcGPXI) can reduce fatty acid, phospholipid, and short chain organic hydroperoxides utilizing a novel redox cycle in which enzyme activity is linked to the reduction of trypanothione, a parasite ...
Docampo, Flohe, Moreno, Viode, Henderson, Walsh, Krauth-Seigel, Muller, Nogoceke, Tetaud, Wilkinson, Wilkinson, Tetaud, Wilkinson, Boveris, Fairlamb, Mehlotra, Carnieri, Kendall, Kelly, Gibson, Martinez-Calvillo, Kelly, Kelly, Kelly, Cannata, Rutter, Easterby, Gommel, Steinert, Sommer, Opperdoes, Opperdoes, Michels, Parsons, Blattner, Bjornstedt, Sztajer, Horiguchi, Holgren, Fabianek, Shih, Shih, van den Bosch, Subramani, Keller, Singh, Singh, Boveris, Duffieux, Goodman, Knoops, Yamashita, Verdoucq, Seo, Lopez, Krieger   +56 more
core   +4 more sources

1,2-Amino oxygenation of alkenes with hydrogen evolution reaction

Nature Communications, 2022
1,2-Aminoxygenation of alkenes without extra oxidant is a practical yet challenging way to prepare β-amino alcohols. Here, the authors report an electro-oxidative route achieving such a goal with H2 evolution, exhibiting broad scope and application ...
Shengzhang Liu, Shengchun Wang, Pengjie Wang, Zhiliang Huang, Tao Wang, Aiwen Lei   +5 more
doaj   +1 more source

Silver and platinum-catalysed addition of O–H and N–H bonds to allenes [PDF]

, 2014
Transition-metal catalysed nucleophile addition to allenes is a very powerful tool for the synthesis of functionalised molecules containing heteroatoms, heterocycles in the intramolecular version, or allyl derivatives in the intermolecular version.
Munoz-Herranz, Maria
core   +1 more source

Synthesis of Trifluoromethylated Monoterpene Amino Alcohols

Molecules, 2022
For the first time, monoterpene trifluoromethylated β-hydroxy-benzyl-O-oximes were synthesized in 81–95% yields by nucleophilic addition of the Ruppert–Prakash reagent (TMSCF3) to the corresponding β-keto-benzyl-O-oximes based on (+)-nopinone ...
Polina A. Petrova, Denis V. Sudarikov, Larisa L. Frolova, Roman V. Rumyantcev, Svetlana A. Rubtsova, Aleksandr V. Kutchin   +5 more
doaj   +1 more source

Synthesis and reactivity of 4-(trifluoromethyl)azetidin-2-ones [PDF]

, 2018
Because of the beneficial effect of a trifluoromethyl group on the biological properties of bioactive compounds on the one hand and the versatile synthetic potential of beta-lactams on the other hand, 4-CF3-beta-lactams comprises interesting entities for
D'hooghe, Matthias, Dao Thi, Hang, Van Nguyen, Tuyen   +2 more
core   +1 more source

Diversity-Oriented Synthesis Based on the DPPP-Catalyzed Mixed Double-Michael Reactions of Electron-Deficient Acetylenes and β-Amino Alcohols

Molecules, 2011
In this study, we prepared oxizolidines through 1,3-bis(diphenylphosphino)-propane (DPPP)–catalyzed mixed double-Michael reactions of b-amino alcohols with electron-deficient acetylenes.
Yi Chiao Fan, Ohyun Kwon
doaj   +1 more source

Influence of Pre-Fermentation Treatments on Wine Volatile and Sensory Profile of the New Disease Tolerant Cultivar Solaris. [PDF]

, 2015
Solaris is a new disease tolerant cultivar increasingly cultivated in cool climate regions. In order to explore the winemaking processes' potential to make different styles of Solaris wines, the effects of different pre-fermentation treatments (direct ...
Liu, Jing, Petersen, Mikael Agerlin, Toldam-Andersen, Torben Bo, Zhang, Shujuan   +3 more
core   +3 more sources

Comparative Investigation of Combined Metabolomics-Flavoromics during the Ripening of Mango (Mangifera indica L.) cv. ‘Nam Dok Mai Si Thong’ and ‘Nam Dok Mai No. 4’

Plants, 2021
A metabolomics-flavoromics approach was conducted to assess the micromolecules of ‘Nam Dok Mai Si Thong’ and ‘Nam Dok Mai No. 4’ mango cultivars from two seasons. During ripening, FAMEs, FFAs, fatty alcohols, sterols, and organic acids were dominant at 0–
Ye Lin Aung, Yaowapa Lorjaroenphon, Pinthip Rumpagaporn, Sudathip Sae-tan, Kriskamol Na Jom   +4 more
doaj   +1 more source