Results 181 to 190 of about 59,395 (233)

Utilization of Fermentation Process for the Production of Novel Plant‐Based Meat Analogs: A Review of Microorganisms, Processing, and Regulations

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT The production of plant‐based meat analogues from various protein sources is an emerging application worldwide, driven by growing population and health concerns. Many microorganisms during fermentation play a crucial role in fermented plant‐based meat alternatives, together with structuring and analytical approaches in terms of nutritional ...
Fatma Beyza Özpınar, Sevda Dere, Serdar Altunay, Osman Sagdic, Enes Dertli   +4 more
wiley   +1 more source

Exceptional Longevity Modifying Allele APOE2 Promotes DNA Signaling Pathways Resisting Cellular Senescence in Human Neurons

Aging Cell, Volume 25, Issue 5, May 2026.
Neurons expressing APOE2 were more resistant to endogenous DNA damage, activated transcriptional signaling pathways associated with DNA repair, and were resilient to stress‐induced DNA damage and cellular senescence. In contrast, APOE4 neurons exhibited elevated expression of rRNA repetitive elements and were prone to becoming senescent.
Cristian Gerónimo‐Olvera, Stephen M. Scheeler, Carlos Galicia Aguirre, Genesis Vega‐Hormazabal, Daniela Garcia, Long Wu, Natalia Murad, Kevin Schneider, Kenneth A. Wilson, Nikola T. Markov, Sicheng Song, Jesse Simons, Akos A. Gerencser, Emily Parlan, Sean D. Mooney, Eric Verdin, Judith Campisi, Tara E. Tracy, David Furman, Simon Melov, Lisa M. Ellerby   +20 more
wiley   +1 more source

Blood‐Based Epigenetic Signatures in Brazilian Males With Alcohol Use Disorder

Addiction Biology, Volume 31, Issue 5, May 2026.
This study represents the first epigenome‐wide association analysis of Alcohol Use Disorder (AUD) in a genetically and culturally diverse Brazilian cohort. Genome‐wide DNA methylation profiling revealed hypomethylation in genes and pathways related to neuronal development, synaptic organization, intracellular signaling and cellular stress responses in ...
Laís da Silva Pereira‐Rufino, Raissa Mazzer de Sino Romano, Regiane Chiavelli Lamim, Rafael Conte, Denise Ribeiro Gobbo, Marcelo Carvalho da Conceição, Vanessa Kiyomi Ota, Lucas Liro, Leslie Domenici Kulikowski, Adriana Marcassa Tucci, Ana Lucia de Moraes Horta, Ana Maria Sebastião, Maria Lucia Oliveira Souza‐Formigoni, João Ricardo Nickenig Vissoci, Alexandre Ferro Aissa, Isabel Cristina Céspedes   +15 more
wiley   +1 more source

Plant perception of β-aminobutyric acid is mediated by an aspartyl-tRNA synthetase. [PDF]

Nat Chem Biol, 2014
Luna E, van Hulten M, Zhang Y, Berkowitz O, López A, Pétriacq P, Sellwood MA, Chen B, Burrell M, van de Meene A, Pieterse CM, Flors V, Ton J.   +12 more
europepmc   +1 more source

14‐3‐3σ up‐regulation in the temporal cortex associates with tau pathology and reactive astroglia in Lewy body disorders

Brain Pathology, Volume 36, Issue 3, May 2026.
14‐3‐3 protein homeostasis is disrupted in Lewy body pathology, showing a diminution of six isotypes and overexpression of stratifin. The latter was associated with stratifin colocalization with tau pathology and reactive astrocytes. Platelets, as a peripheral biomarker source, mirrored inversely cortical 14‐3‐3 gene expression patterns in dementia ...
Laura Marsal‐García, Jorge Mena, Carol‐Ann Lao, David Adamuz, Laura Arnaldo, Cristina Carrato, Alex Menendez, Daniela Samaniego, Dolores Vilas, Lourdes Ispierto, Anna Planas, Ramiro Alvarez, Pau Pastor, Katrin Beyer   +13 more
wiley   +1 more source

Epigenetic analyses suggest different pathways during pregnancy for development of type 1 diabetes in children with high versus low‐neutral human leukocyte antigen‐risk

Journal of Internal Medicine, Volume 299, Issue 5, Page 570-586, May 2026.
Abstract Background and objective The development of Type 1 diabetes (T1D) is shaped by genetic predisposition and epigenetic regulation. Human leukocyte antigen (HLA) risk alleles are major genetic determinants, but the epigenetic landscape in relation to disease onset remains unclear.
Shamila D. Alipoor, Angelica Ahrens, Julia Åkesson, Thomas Hillerton, Mika Gustafsson, Maria Lerm, Johnny Ludvigsson   +6 more
wiley   +1 more source

The C2H2‐GGAT Regulatory Module Fine‐Tunes Glutamate Homeostasis to Improve Fruit Flavour and Enhance Disease Resistance in Peach

Plant Biotechnology Journal, Volume 24, Issue 5, Page 3282-3295, May 2026.
ABSTRACT Free amino acids (FAAs) play a fundamental role in determining fruit quality and stress adaptation, yet their genetic regulation remains poorly understood. Through an integrated approach combining metabolomic and sensory analyses of 120 peach (Prunus persica) hybrids, we identified glutamate as a key metabolite linking FAA content to umami ...
Yike Su, Xiaojuan Yang, Chanyuan Wu, Xianyao Jin, Yuanyuan Zhang, Yuyan Zhang, Kunsong Chen, Mingliang Yu, Bo Zhang   +8 more
wiley   +1 more source

Altered spectral patterns of aperiodic electroencephalography in autism

Psychiatry and Clinical Neurosciences, Volume 80, Issue 5, Page 423-431, May 2026.
Aim The altered ratio of neural excitation (E) and inhibition (I) has been proposed to the etiology of autism spectrum disorder (ASD). Previous studies suggested a lower E/I ratio in autistic individuals compared to non‐autistic comparisons (NACs) in specific brain regions.
Yi‐Ling Chien, Ming Hsien Hsieh, Yi‐Hsuan Hsieh, Yi‐Li Tseng   +3 more
wiley   +1 more source

Comparative study on changes in serum amino acid metabolic profiles in mice exposed to perfluorooctanoic acid and sodium ρ-perfluorous nonenoxybenzene sulfonate. [PDF]

Sci Rep
Guo X, Jing N, Liang S, Wei Q, Cui W, Xiao Y, Yang H, Wang F.   +7 more
europepmc   +1 more source

Bacteria as Passive Passengers in the Equatorial Pacific Biological Carbon Pump

Geophysical Research Letters, Volume 53, Issue 8, 28 April 2026.
Abstract Bacteria are important agents modulating the efficiency of the ocean's biological carbon pump (BCP). The long‐standing view considers bacteria as degraders of sinking particulate organic carbon (POC), yet underappreciates their contribution to carbon export.
Jinqiang Guo, Huamao Yuan, Yao Gao, Eric P. Achterberg, Frédéric A. C. Le Moigne, Rainer Kiko, Yuan Shen   +6 more
wiley   +1 more source