Results 41 to 50 of about 3,283,667 (179)

An autocrine role for pituitary GABA: Activation of GABA-B receptors and regulation of growth hormone levels [PDF]

, 2002
There is increasing evidence suggesting that the neurotransmitter gamma-aminobutyric acid (GABA) is a local factor involved in the regulation of endocrine organs.
Corsi, C., Pepeu, G., Gratzl, M., Gamel-Didelon, Katia, Jung, H., Mayerhofer, Artur   +5 more
core   +1 more source

Combination of β-Aminobutyric Acid and Ca2+ Alleviates Chilling Stress in Tobacco (Nicotiana tabacum L.)

Frontiers in Plant Science, 2020
Chilling is a major abiotic factor limiting the growth, development, and productivity of plants. β-aminobutyric acid (BABA), a new environmentally friendly agent, is widely used to induce plant resistance to biotic and abiotic stress.
Xiao-Han Ma, Jia-Yang Xu, Dan Han, Wu-Xing Huang, Bing-Jun Dang, Wei Jia, Zi-Cheng Xu   +6 more
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw, Karishma Randhave, Ekta Anand, Ziang (Debbie) Song, Wangzhen Shen, Jing‐Qiong Kang   +5 more
wiley   +1 more source

Priming: Getting Ready for Battle

Molecular Plant-Microbe Interactions, 2006
Infection of plants by necrotizing pathogens or colonization of plant roots with certain beneficial microbes causes the induction of a unique physiological state called “ priming”.
Uwe Conrath, Gerold J. M. Beckers, Victor Flors, Pilar García-Agustín, Gábor Jakab, Felix Mauch, Mari-Anne Newman, Corné M. J. Pieterse, Benoit Poinssot, María J. Pozo, Alain Pugin, Ulrich Schaffrath, Jurriaan Ton, David Wendehenne, Laurent Zimmerli, Brigitte Mauch-Mani   +15 more
doaj   +1 more source

Gut Microbial Release of Ferulic Acid From Germinated Quinoa Alleviates Obesity‐Associated Cognitive Impairment by Activating Hippocampal Mitophagy Associated with PINK1/Parkin Pathway

Advanced Science, EarlyView.
Liberation of ferulic acid by gut microbial feruloyl esterase mediates cognitive enhancement of germinated quinoa (GQF) on obese mice. Ferulic acid enriched in GQF is released by gut microbes Roseburia hominis and R. intestinalis and subsequently mediates the neuroprotective effects of GQF on obesity‐induced cognitive decline by activating hippocampal ...
Yongli Lan, Wengang Zhang, Lei Wang, Shiyang Zhao, Yujie Song, Xinze Wang, Yutang Wang, Xijuan Yang, Shaobo Ma, Junlin Ge, Rui Guo, Xuebo Liu   +11 more
wiley   +1 more source

When the story proceeds backward: The discovery of endogenous β-aminobutyric acid as the missing link for a potential new plant hormone

Communicative & Integrative Biology, 2017
The capacity of β-aminobutyric acid (BABA) to induce resistance in plants against biotic and abiotic stresses has been known for more than 50 y. In the beginning reports were mainly descriptive of the phenomenon, but it became clear with the discovery of
Ivan Baccelli, Brigitte Mauch-Mani
doaj   +1 more source

The last link of the x-aminobutyric acid series: the five conformers of β-aminobutyric acid

, 2018
Structural characterization of β-aminobutyric acid by rotational spectroscopy.
C. Cabezas, E. R. Alonso, I. León, J. L. Alonso, I. Peña   +4 more
core   +1 more source

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

Advanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He, Yuwen Wang, Jonathan F. Gong, Yiting Lei, Fei Jin, Weihong Zhu, Rocky S. Tuan, Zhong Alan Li   +7 more
wiley   +1 more source

β-Aminobutyric Acid-induced Resistance in Plants [PDF]

, 2001
The broad sprectrum protective effect of the non-protein amino acid β-aminobutyric acid (BABA) against numerous plant diseases has been well-documented in the literature.
Toquin, Valérie, Zimmerli, Laurent, Mauch-Mani, Brigitte, Métraux, Jean-Pierre, Cottier, Valérie, Jakab, Gabor, Rigoli, Ghislaine   +6 more
core   +1 more source

EphB1 Receptor Blockade Augments Morphine Antinociception via Inhibiting GRK2‐Mediated µ‐Opioid Receptor Internalization

Advanced Science, EarlyView.
Administration of opioids activates ephrinB2‐EphB1 receptor signaling. Activated EphB1 receptors induce GRK2‐mediated phosphorylation of MOR at Ser375, which initiates the internalization of MOR and reduces opioid antinociception at the behavioral level. ABSTRACT Opioids are the primary treatment for severe pain in clinical practice.
Bo Peng, Xiaqing Lin, Hongyu Yao, Cheng Li, Huabao Liao, Yuexin Liu, Boxu Cao, Xue‑Jun Song   +7 more
wiley   +1 more source