Results 91 to 100 of about 18,849 (159)

Mechanistic insights into the versatile stoichiometry and biased signaling of the apelin receptor-arrestin complex

Nature Communications
The apelin receptor (APJR) plays a pivotal role in regulating cardiovascular and metabolic health1,2. Understanding the mechanisms of biased agonism at APJR is crucial for drug discovery, as stimulation of the β-arrestin pathway may lead to some adverse ...
Yang Yue, Chanjuan Xu, Lijie Wu, Man Na, Kexin Xu, Xuan Chen, Yuxuan Song, Sichun Weng, Lu Xu, Fei Li, Xi Lin, Arthur Wang, Jianfeng Liu, Fei Xu   +13 more
doaj   +1 more source

β-Arrestin-2 Regulates Sodium Taste Processing. [PDF]

Hypertension
Grobe CC, Hamilton AJ, Treesukosol Y, Grobe JL, Segar JL, Sigmund CD.   +5 more
europepmc   +1 more source

Membrane cholesterol modulates engagement of β-arrestin with the ghrelin receptor. [PDF]

Commun Biol
Berto L, Henri P, Damian M, Cantel S, Fehrentz JA, Sibille N, Di Michele M, Banères JL.   +7 more
europepmc   +1 more source

Dynamic Pathway Selectivity of TAS2R5 toward or Away from β-Arrestin or G Protein from Biased Agonists. [PDF]

Biochemistry
Kim D, Strzelinski HR, Longabardi CM, Liggett SB.   +3 more
europepmc   +1 more source

GRK phosphorylation drives β-arrestin-independent internalization of chemokine receptor CXCR5. [PDF]

J Biol Chem
Crecelius JM, Zhuo Y, Manz AR, Drube J, Schulz S, Hoffmann C, Marchese A.   +6 more
europepmc   +1 more source

Knowledge graph and emerging trends in β-arrestin research on pain: a bibliometric analysis (1997-2025). [PDF]

Naunyn Schmiedebergs Arch Pharmacol
Yu H, Ding X, Zhang Y, Yu Y, Wang X.
europepmc   +1 more source

Functional and structural insights into interactions between β-Arrestin 1 and Gαs or Gαi1. [PDF]

Nat Commun
Duan L, Kim H, Suh Y, Ahn D, Kim S, Hyun J, Kwon Y, Seong J, Chung KY.   +8 more
europepmc   +1 more source

Angiotensin receptor conformations stabilized by biased ligands differentially modulate β-arrestin interactions. [PDF]

J Biol Chem
Elgeti M, Belyaeva J, Helabad MB, Staus DP, Wingler LM.   +4 more
europepmc   +1 more source

β-Arrestin 1 Differentially Modulates cAMP and ERK Pathways Downstream of the FSH Receptor. [PDF]

Curr Issues Mol Biol
Park SH, Byambaragchaa M, Yu YR, Lee JW, Kwak MJ, Yoon SB, Kim JS, Kang MH, Min KS.   +8 more
europepmc   +1 more source

PAR2-β-arrestin 2-ERK axis mediates <i>Malassezia globosa</i>-induced IL-17 response by disrupting ZO-1 in keratinocytes. [PDF]

iScience
Tang J, Li F, Hong J, Li X, Zhou Y, Liu J, Fan Y.   +6 more
europepmc   +1 more source