Results 131 to 140 of about 29,885 (192)

Host versus cell-dependent effects of β-arrestin 1 expression in prostate tumorigenesis. [PDF]

Carcinogenesis, 2021
Adekoya TO, Smith N, Thomas AJ, Lane TS, Burnette N, Rivers EJ, Li Y, Chen XL, Richardson RM.   +8 more
europepmc   +1 more source

GRKs and arrestins: Nomenclature and functions in GPCR‐dependent and ‐independent signalling

British Journal of Pharmacology, Volume 183, Issue 11, Page 2619-2633, June 2026.
G protein‐coupled receptor (GPCR) kinases (GRKs) and arrestins play a critical role in the regulation of GPCR signalling. Historic names of mammalian GRKs were replaced by systematic ones in the 1990s; however, both kinds of names are currently in use for mammalian arrestins.
Vsevolod V. Gurevich
wiley   +1 more source

β-arrestin biased signaling is not involved in the hypotensive actions of 5-HT7 receptor stimulation: use of Serodolin

Pharmacological Research
The 5-hydroxytryptamine 7 receptor (5-HT7) is necessary for 5-HT to cause a concentration-dependent vascular relaxation and hypotension. 5-HT7 is recognized as having biased signaling, transduced through either Gs or β -arrestin.
Stephanie W. Watts, Hannah Garver, Severine Morisset-Lopez, Franck Suzenet, Gregory D. Fink   +4 more
doaj   +1 more source

Opposing functions of β-arrestin 1 and 2 in Parkinson's disease via microglia inflammation and Nprl3. [PDF]

Cell Death Differ, 2021
Fang Y, Jiang Q, Li S, Zhu H, Xu R, Song N, Ding X, Liu J, Chen M, Song M, Ding J, Lu M, Wu G, Hu G.   +13 more
europepmc   +1 more source

c‐Jun N‐terminal kinase 3 as a permissive regulator of β‐cell incretin responsiveness

Journal of Diabetes Investigation, Volume 17, Issue 6, Page 915-916, June 2026.
Yuji Yamazaki
wiley   +1 more source

Single‐Cell Sequencing Reveals That CCL2+ Adipose‐Derived Stem Cells Promote Diabetic Wound Healing Through the CCL2‐ACKR1 Signaling Axis

The FASEB Journal, Volume 40, Issue 9, 15 May 2026.
scRNA‐seq of human adipose and diabetic wounds revealed a CCL2+ ADSC subpopulation with high stemness and ECM‐enriched pathways. These cells serve as a signaling hub via TGFB1‐TGFBR1, IL34‐CSF1R, and CCL2‐ACKR1. Their exosomes (CCL2‐Exos), carrying CCL2, TGFB1, and IL34, accelerate diabetic wound healing in mice by promoting angiogenesis, collagen ...
Songyun Zhao, Wanying Chen, Kaibo Liu, Jiaheng Xie, Yanming Chen, Hao Dai, Zhongqiu Lu, Longwang Chen, Yucang He, Hua Yu, Liqun Li   +10 more
wiley   +1 more source

β-Arrestin-1 is required for adaptive β-cell mass expansion during obesity. [PDF]

Nat Commun, 2021
Barella LF, Rossi M, Pydi SP, Meister J, Jain S, Cui Y, Gavrilova O, Fulgenzi G, Tessarollo L, Wess J.   +9 more
europepmc   +1 more source

β-arrestin/connexin 43 complex anchors ERKs outside the nucleus: a pre-requisite for bisphosphonate anti-apoptotic effect mediated by CX43/ERK in osteocytes [PDF]

, 2016
Bisphosphonates (BPs) anti-fracture ef cacy may be due in part to inhibition of osteocyte apoptosis. This effect requires opening of con- nexin (Cx) 43 hemichannels and phosphoryla- tion of the extracellular signal regulated kinases (ERKs).
Bellido, Teresita, Gortazar, Arancha R., Plotkin, Lilian I.   +2 more
core  

Intersections between Copper, β-Arrestin-1, Calcium, FBXW7, CD17, Insulin Resistance and Atherogenicity Mediate Depression and Anxiety Due to Type 2 Diabetes Mellitus: A Nomothetic Network Approach. [PDF]

J Pers Med, 2022
Al-Hakeim HK, Hadi HH, Jawad GA, Maes M.
europepmc   +1 more source

Structure of the neurotensin receptor 1 in complex with β-arrestin 1. [PDF]

Nature, 2020
Huang W, Masureel M, Qu Q, Janetzko J, Inoue A, Kato HE, Robertson MJ, Nguyen KC, Glenn JS, Skiniotis G, Kobilka BK.   +10 more
europepmc   +1 more source