Results 111 to 120 of about 49,242 (209)

A Model of Demasking and Hydrolysis of Peptide Bonds During Tryptic Digestion of β-Casein and β-Lactoglobulin. [PDF]

Molecules
Vorob'ev MM.
europepmc   +1 more source

Retinoic Acid‐Related Orphan Nuclear Receptor Alpha Promotes Cartilage Degeneration in Osteoarthritis by Activating the Wnt/β‐Catenin Pathway

The FASEB Journal, Volume 40, Issue 11, 15 June 2026.
During the development of OA, elevated RORα in chondrocytes inhibits β‐catenin degradation in the cytoplasm by activating the Wnt/β‐catenin signaling pathway. When β‐catenin protein accumulates excessively in the cytoplasm, it is transferred to the nucleus and binds to the cytosolic TCF/LEF transcriptional complex, which activates downstream target ...
Ruijue Zhu, Tianwei He, Jiawei Di, Lang Mai, Depeng Wu, Mudan Huang, Yankui Liu, Zhongyu Liu, Liangming Zhang, Lei He   +9 more
wiley   +1 more source

Frequency of A1 and A2 alleles of the β-casein gene in cattle in the Cajamarca region of Peru. [PDF]

Open Vet J
Becerra-Quiroz AL, Rivera-Jacinto MA, Cueva-Rodríguez M, Tayca-Saldaña A, Alvarez-García W, Quilcate-Pairazamán C, Bazán-Arce J, Torres-Caruajulca VG, Cabrera-González M.   +8 more
europepmc   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, Volume 13, Issue 35, 24 June 2026.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Characterizing detectable milk protein allergens β-casein and β-lactoglobulin in milk ladder foods. [PDF]

Pediatr Allergy Immunol
Simmons R, Vennard TR, Gaygadzhiev Z, Cano N, Gray MA, Meyer R, Venter C.   +6 more
europepmc   +1 more source

Gastric Emptying of New-World Milk Containing A1 and A2 Β-Casein Is More Rapid as Compared to Milk Containing Only A2 Β-Casein in Lactose Maldigesters: A Randomized, Cross-Over Trial Using Magnetic Resonance Imaging. [PDF]

Nutrients, 2023
Ramakrishnan M, Zhou X, Dydak U, Savaiano DA.   +3 more
europepmc   +1 more source

A Rational Optimization Approach for the Development of a Multiplexed Lateral Flow Immunoassay: Detection of Nonepithelial Ovarian Cancer Markers in Human Serum

Advanced Science, Volume 13, Issue 31, 4 June 2026.
This study outlines the developmental pipeline of a multiplexed nanozyme‐based lateral flow immunoassay for the purpose of ovarian germ cell tumor detection. It demonstrates the application of a design of experiments optimization approach for nanozyme probe conjugate development.
Aida Abdelwahed, Carl E. Eskildsen, Luca Panariello, André Shamsabadi, Christy J. Sadler, Edmund H. Wilkes, Federico Galvanin, Yuxi Cheng, Sara Carvalho, Srdjan Saso, Molly M. Stevens   +10 more
wiley   +1 more source

Modification of a previously patented method to unequivocally score A2-like and A1-like bovine β-casein variants. [PDF]

MethodsX, 2023
Raschia MA, Caffaro ME, Rossi ÚA, Poli MA.   +3 more
europepmc   +1 more source

Genetic Diversity of the Beta‐Casein Gene in Brown Swiss and Creole Cattle From the Peruvian Highlands

Animal Genetics, Volume 57, Issue 3, June 2026.
ABSTRACT Cattle's milk and derivatives are essential for human nutrition. However, up to 90% of people experience gastrointestinal discomfort after consumption. Milk digestibility depends on its protein composition. Casein, about 80% of milk proteins, includes beta‐casein (CSN2) with two variants: A1 and A2. The A1 variant is linked to gastrointestinal
Lucy R. Remigio Lorenzo, Cristina Rivera Romero, Joao De Souza Pacheco, Wilder Bueno Cabrera, Eduardo L. Fuentes Navarro, Rudolf Pichler, Kathiravan Periasamy, Gustavo A. Gutiérrez‐Reynoso   +7 more
wiley   +1 more source

Dual-Phase Immunomodulation by the Bovine β-Casein Peptide KEMPFPK: Insights into Potential TLR Interaction and Gut Microbiota-Mediated Effects. [PDF]

Foods
Zhang J, Zhang X, Wu J, Mu G, Wu X.
europepmc   +1 more source