Results 121 to 130 of about 947,788 (251)
Targeting CKIP‐1 for Disease Therapy: Cellular Functions, Molecular Networks, and Clinical Potential
Cell Proliferation, EarlyView.CKIP‐1, as a scaffold protein with special structural domains, treats related diseases through multiple emerging targeted technologies.
Xin Huang +4 more
wiley +1 more source
Effect of genetic polymorphism on the thermal stability β-Lactoglobulin and K-Casein mixture
, 1991 The effect of calcium chloride and genetic variants of K-casein on the thermal stability of P-lactoglobulin isolated from bovine milk of known genetic types was investigated using differential scanning calorimetry.
Imafidon, IG +7 more
core +1 more source
S‐Adenosylmethionine (SAM) hydrolases counter increased SAM epimerisation in thermophilic archaea
The FEBS Journal, EarlyView.S‐Adenosyl‐l‐methionine (SAM) is a vital enzyme cofactor. Epimerisation at the sulfonium centre of biologically active (SS,SCα)‐SAM is driven by heat, yielding biologically inactive (RS,SCα)‐SAM. Here, two novel archaeal SAM hydrolases from the thermophilic Sulfolobus acidocaldarius and the halophilic Haloferax volcanii are shown to cleave (RS,SCα)‐SAM.
Agnes Bartels +7 more
wiley +1 more source
The FEBS Journal, EarlyView.Okur‐Chung neurodevelopmental syndrome (OCNDS) is a neurodevelopmental disorder associated with mutations in the gene coding for Protein kinase CK2α. In this work, 42 variants of CK2α associated with OCNDS were characterized in vitro. This included determination of catalytic activity and CK2α/CK2β‐interaction as well as an assessment of evolutionary ...
Alexander Gast +3 more
wiley +1 more source
Genotypic profiling of A1 and A2 β-casein alleles in Punganur cattle using PCR-RFLP
Indian Journal of Animal SciencesMilk is regarded as nature’s perfect food due to the presence of essential nutrients required for the growth and development of mammals. The consumption of milk with a specific β casein variant either A1 or A2 had a relationship with the risk of ...
AVINASH P +2 more
doaj +1 more source
Expression and Purification of Glycosylated Bovine β-Casein (L70S/P71S) in Pichia Pastoris
, 2001 Post-translational glycosylation of bovine β -casein (L70S/P71S) that results in Asn68-linked glycan on the protein was obtained in up to 30% of total β-casein expressed in the methylotrophic yeast Pichia pastoris.
Choi, Byung-Kwon +1 more
core +1 more source
PEG400 regulates Falcipain 2 activity through an allosteric mechanism
The FEBS Journal, EarlyView.Falcipain‐2 can potentially be leveraged as a drug target due to its critical role as a haemoglobinase during the intra‐erythrocytic stage of Plasmodium falciparum. Here, we investigate the regulation of the proteolytic and haemoglobinase activity of falcipain‐2 in the presence of polyethylene glycol.
Bikram Nath +2 more
wiley +1 more source
Molecular Microbiology, EarlyView.Abbreviated Summary The role of the major fungal cell wall polymer α‐1,3‐glucan in plant infection is poorly understood. Deletion mutants of the maize anthracnose fungus Colletotrichum graminicola lacking all three α‐1,3‐glucan synthase genes differentiated severely distorted biotrophic hyphae in planta, and virulence was strongly reduced.
Iris Gase +13 more
wiley +1 more source
Neonatal Gut and Immune Responses to β-Casein Enriched Formula in Piglets
Background: β-casein is the main casein constituent in human milk (HM) and a source of bioactive peptides for the developing gastrointestinal tract and immune system.
Ghisari, Mandana +7 more
core +1 more source
Engineered surface strategies to manage dental implant‐related infections
Periodontology 2000, EarlyView.Abstract When exposed to the oral environment, dental implants, like natural surfaces, become substrates for microbial adhesion and accumulation, often leading to implant‐related infections—one of the main causes of implant failure. These failures impose significant costs on patients, clinicians, and healthcare systems.
João Gabriel S. Souza +7 more
wiley +1 more source