Results 371 to 380 of about 1,680,534 (386)

Roles of β-catenin protein in non-small cell lung cancer (Review). [PDF]

Oncol Lett
Peng L, Gao R, Han L, Fu T, Bian C.
europepmc   +1 more source

β-catenin condensation facilitates clustering of the cadherin/catenin complex and formation of nascent cell-cell junctions. [PDF]

Nat Commun
Monster JL, Manzato C, van der Beek JA, Pannekoek WJ, Hummelink JA, Hadders MA, de Heus C, Klumperman J, Schuijers J, Gloerich M.   +9 more
europepmc   +1 more source

Astaxanthin inhibits hepatocellular carcinoma by targeting USP39-mediated β-catenin stabilization through deubiquitination. [PDF]

Sci Rep
Li X, Xu H, Chen R, Huang X, Lin Z, Wang S, Han L, Li J, Lin L, Qi Y, Song G, Song C.   +11 more
europepmc   +1 more source

Albiflorin enhances the antitumor effects of propofol in hepatocellular carcinoma cells by inhibiting the Wnt/β-catenin signaling activation. [PDF]

Transl Cancer Res
Ji T, Ye L, Xu C, Ma C, Yin G.
europepmc   +1 more source

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Design and synthesis of selective inhibitors for β-catenin/t-cell factor-4 protein-protein interaction

2018
Selective disruption of protein-protein interactions by small molecules is important for probing the structure and dynamic aspects of the cellular network. It can also provide new therapeutic targets. β-Catenin of the canonical Wnt signaling pathway uses the same positively charged groove to bind with T-cell factor (Tcf), cadherin, and adenomatous ...
openaire   +1 more source

Toward better development of protein-protein interaction inhibitors: applications to the β-catenin/t-cell factor protein-protein interaction

2018
The dysregulation of proteinâ€"protein interaction (PPI) networks has been implicated in many diseases. Designing therapeutic small-molecule inhibitors of these interactions is a challenging field for medicinal chemistry. This work advances the techniques for discovering more potent PPI inhibitors through integration of computational and biochemical ...
openaire   +1 more source

Intestinal Crypt Fission and Expression of Î'-Catenin in the Small Intestine of Humans

Gastroenterology, 2017
Zenab M. Dudhwala, Gordon S. Howarth, Paul Drew, David Moore, Adrian G. Cummins   +4 more
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Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity

Nature, 2015
S. Spranger, R. Bao, T. Gajewski
semanticscholar   +1 more source