Results 41 to 50 of about 23,485 (167)

The profile of lysosomal exoglycosidases in replicative and stress-induced senescence in early passage human fibroblasts

Folia Histochemica et Cytobiologica, 2012
The aim of the present study was to assess the profiles of the exoglycosidases: N-acetyl-β-hexosoaminidase, β glucuronidase and β galactosidase, α mannosidase and α fucosidase in fibroblast culture undergoing replicative and stress-induced senescence ...
Małgorzata Knaś, Anna Zalewska, Rafał Krętowski, Marek Niczyporuk, Napoleon Waszkiewicz, Marzanna Cechowska-Pasko, Danuta Waszkiel, Krzysztof Zwierz   +7 more
doaj   +1 more source

Bioactivation and Metabolism of Amino Acid MDMA Prodrugs in Zebrafish Embryos, Human Liver S9, Whole Blood, and Microdosed Human Urine

Drug Testing and Analysis, EarlyView.
Bioactivation and metabolism of MDMA prodrugs: MDMA‐Trp, MDMA‐Lys, MDMA‐Gly showed unique urine screening targets only for MDMA‐Trp, while biomarkers for MDMA‐Lys and MDMA‐Gly consisted of MDMA and known MDMA metabolites. Conversion of amino acid prodrugs to MDMA in pHLS9, zebrafish embryos, and humans. ABSTRACT 3,4‐Methylenedioxymethamphetamine (MDMA)
Simon K. Wellenberg, Lea Wagmann, Matthias D. Kroesen, Philip Schippers, Matthias Grill, Jennifer Herrmann, Markus R. Meyer   +6 more
wiley   +1 more source

Evaluation of Different Detection and Identification Methods of Intact Tetrahydro‐Methyltestosterone Sulfate Metabolites in Doping Control

Drug Testing and Analysis, EarlyView.
The micro‐scale synthesis of the six out of eight possible tetrahydro‐methyltestosterone sulfate metabolites was performed, and the synthesized materials were used as analytical standards. The analysis of post‐administration sample extracts from methyltestosterone excretion studies against these standards provides further experimental proof for their ...
Yiannis S. Angelis, Olga Goula, Polyxeni Kiousi, Panagiotis Sakellariou   +3 more
wiley   +1 more source

Incidence of Escherichia coli  - Glucuronidase Positive on Goat Milk

Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca: Agriculture, 2016
Papers on beta- glucuronidase sensitivity and specificity for identifying Escherichia coli in sources of environment, food, water, etc. have been published since 1976. In this study we conducted a review of the incidence of E.
Zorica Voşgan, Anca Domuţa, Stela Jelea, Lucia Mihălescu, Flavia Pop   +4 more
doaj   +1 more source

Biomass‐derived hydrochars as eco‐friendly adsorbents for wastewater treatment applications

Environmental Progress &Sustainable Energy, EarlyView.
Abstract Emerging organic pollutants (EOPs), such as diethyl phthalate (DEP), bisphenol A (BPA), and methylene blue (MB), are only partially removed in conventional wastewater treatment plants. This study assesses hydrochars produced by hydrothermal carbonization (HTC) of spruce bark (SB), vine shoots (VSs), and wheat straw (WSs) for removing three ...
Emanuel Gheorghita Armanu, Sara Ribeirinho‐Soares, Christian Eberlein, Hermann J. Heipieper, Irina Volf, Olga C. Nunes, Olívia Salomé G. P. Soares   +6 more
wiley   +1 more source

Investigation of the inhibitory potential of secondary metabolites isolated from Fernandoa adenophylla against Beta-glucuronidase via molecular docking and molecular dynamics simulation studies.

PLoS ONE
Elevated β-glucuronidase activity is associated with the production of toxic metabolites that contribute to tumor development and other diseases. Inhibiting this enzyme may offer therapeutic potential, including the prevention of colonic carcinogenesis ...
Abdur Rauf, Rahaf Ajaj, Zuneera Akram, Majid Khan, Abdul Wadood, Maryam Zulfat, Zafar Ali Shah, Abdulhakeem S Alamri, Walaa F Alsanie, Majid Alhomrani, Humaira Hussain, Dorota Formanowicz   +11 more
doaj   +1 more source

Mitochondrial dysfunction leads to deconjugation of quercetin glucuronides in inflammatory macrophages. [PDF]

PLoS ONE, 2013
Dietary flavonoids, such as quercetin, have long been recognized to protect blood vessels from atherogenic inflammation by yet unknown mechanisms. We have previously discovered the specific localization of quercetin-3-O-glucuronide (Q3GA), a phase II ...
Akari Ishisaka, Kyuichi Kawabata, Satomi Miki, Yuko Shiba, Shoko Minekawa, Tomomi Nishikawa, Rie Mukai, Junji Terao, Yoshichika Kawai   +8 more
doaj   +1 more source

Bioengineered Isoflavone–Probiotic Functional Foods for Sustainable Modulation of Metabolic and Reproductive Health in PCOS

Food Bioengineering, EarlyView.
Synergistic isoflavone‐probiotic action modulated metabolic, microbial and ovarian pathway ABSTRACT Polycystic ovary syndrome (PCOS) is a prevalent metabolic–endocrine disorder characterized by insulin resistance, hyperandrogenism, chronic inflammation, oxidative stress, and ovarian dysfunction, with growing evidence implicating gut microbiota ...
Jeyavelkumaran Renukadevi, Panneerselvam Sneha, Dhanapal Saravanan Mridula, Keerthivasan Nimithasree, Valliappan Sanjay   +4 more
wiley   +1 more source

Musa balbisiana and Musa paradisiaca Starches Increase SCFA and Caspase-3 as well as Decrease β-glucuronidase and MDA of Mouse Model for Colon Cancer

Indonesian Biomedical Journal, 2021
BACKGROUND: Administration of resistant starch (RS) influences the diversity and the composition of microbiota as well as inhibits the growth of cancer cell. Banana as a potential source of RS has been reported.
Diana Nur Afifah, Fauzia Purnamasari, Luthfiatul Khusna, Noviasti Rahma Utami, Aida Fitri Nazillah, Syafira Noor Pratiwi, Fillah Fithra Dieny, Aryu Candra, Ayu Rahadiyanti, Rachma Purwanti, Enny Probosari, Martha Ardiaria, Nyoman Suci Widiastiti, Ferry Sandra   +13 more
doaj   +1 more source

Current Advancements of Probiotic Foods and Their Role in Sustainable Food Security

Food Bioengineering, EarlyView.
ABSTRACT Probiotic foods have evolved from traditional fermented products to scientifically validated functional foods, defined by the FAO and WHO as live microorganism that confer a health benefit on the host when administered in adequate amounts, with effects being strain, does and end point specific.
Ashenafi Teklay Yaekob, Gebremedhin Gebreslassie, Etsay Mesele, Tesfakiros Semere   +3 more
wiley   +1 more source