Results 41 to 50 of about 2,563,124 (253)

Isolation and Structural Characterization of Specific Bacterial β-Glucuronidase Inhibitors from Noni (Morinda citrifolia) Fruits.

Journal of Natural Products, 2020
An extract of noni (Morinda citrifolia) fruits has shown potent inhibitory activity on gut bacterial β-glucuronidase, which could help reduce irinotecan-induced diarrhea.
Fei Yang, Wen-Jun Zhu, Shi Sun, Qing Ai, Paba Edirisuriya, K. Zhou   +5 more
semanticscholar   +1 more source

MOESM1 of Indole bearing thiadiazole analogs: synthesis, β-glucuronidase inhibition and molecular docking study

, 2019
Additional file 1. Supporting data having proton NMR of all compounds.
Almandil, Noor, Taha, Muhammad, Gollapalli, Mohammed, Rahim, Fazal, Ibrahim, Mohamed, Mosaddik, Ashik, Anouar, El   +6 more
openaire   +1 more source

The role of the host—Neutrophil biology

Periodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple, Josefine Hirschfeld, Alpdogan Kantarci, Asaf Wilensky, Lior Shapira   +4 more
wiley   +1 more source

Lactate Dehydrogenase and β-Glucuronidase as Salivary Biochemical Markers of Periodontitis Among Smokers and Non-Smokers

Sultan Qaboos University Medical Journal, 2018
Objectives: This study aimed to establish lactate dehydrogenase (LDH) and β-glucuronidase as salivary biomarkers of periodontitis among smokers and non-smokers.
Syed A. Ali, Ravi L. Telgi, Amit Tirth, Irfan Q. Tantry, Abdul Aleem   +4 more
doaj   +1 more source

Supplementation with a Probiotic Formula Having β-Glucuronidase Activity Modulates Serum Estrogen Levels in Healthy Peri- and Postmenopausal Women

Journal of Medicinal Food
Declines in estrogen levels occur in women transitioning to menopause. Estrogen hormones play important roles in multiple systems of the body, and estrogen loss is associated with a variety of symptoms that can decrease quality of life.
Shinichi Honda, Yuji Tominaga, J. Espadaler-Mazo, P. Huedo, Meritxell Aguiló, Marta Perez, Takahiro Ueda, J. Sawashita   +7 more
semanticscholar   +1 more source

Bridging in silico and in vitro perspectives to unravel molecular mechanisms underlying the inhibition of β-glucuronidase by coumarins from Hibiscus trionum.

Biophysical Chemistry
Unraveling the intricacies of β-glucuronidase inhibition is pivotal for developing effective strategies in applications specific to gastrointestinal health and drug metabolism.
Emadeldin M. Kamel, Faris F. Aba Alkhayl, H. Alqhtani, M. Bin-Jumah, H. Rudayni, A. M. Lamsabhi   +5 more
semanticscholar   +1 more source

Native β-glucuronidase electrophoresis and activity assays.

, 2015
(A) E. coli β-glucuronidase (0.05, 0.5, 5, and 50 μg) was electrophoresed under native conditions, followed by 30-minute incubation with X-GlcA at room temperature (B). Oligomeric forms of β-glucuronidase are labeled.
Kimberly T. Lane (762232), Charles G. Folsom (762231), Gina G. Burchett (762230)   +2 more
core   +1 more source

Dissecting molecular mechanisms underlying the inhibition of β-glucuronidase by alkaloids from Hibiscus trionum: Integrating in vitro and in silico perspectives

Comput. Biol. Medicine
β-Glucuronidase, a crucial enzyme in drug metabolism and detoxification, represents a promising target for therapeutic intervention due to its potential to modulate drug pharmacokinetics and enhance therapeutic efficacy.
Emadeldin M. Kamel, F. Alkhayl, H. Alqhtani, M. Bin-Jumah, H. Rudayni, A. M. Lamsabhi   +5 more
semanticscholar   +1 more source

In vivo random β-glucuronidase gene fusions in Arabidopsis thaliana

, 1991
Vectors were constructed for the isolation of random transcriptional and translational β-glucuronidase gene fusions in plants. This system is based on the random integration of the transferred DNA (T-DNA) into the plant nuclear genome.
Deboeck, Francine, Kertbundit, Sunee, Hernalsteens, Jean-Pierre, Van Montagu, Marc, De Greve, Henri   +4 more
core   +1 more source

Studies on β- Glucuronidase enzyme inhibition and insecticidal activity from Echinops Echinatus

, 2020
β-glucuronidase is a common enzyme which cleaves in β linkage and converts aglycone to a glucuronic acid. Studies have been made on this enzyme and a lot of work has been reported about specific inhibition of β-glucuronidase enzyme and insecticidal ...
Khawar Saeed, Aftab Yaseen, Muhammad Kashif Zaman, Muhammad Uzair   +3 more
core   +1 more source