Results 161 to 170 of about 1,046,387 (249)

Insight into β-Hairpin Stability: Interstrand Hydrogen Bonding

open access: yes, 2013
For evaluation of the role of interstrand hydrogen bonding for -hairpin stability, two cyclic peptides differing only in side chain hydroxy-to-methyl substitution were designed and synthesized on solid phase following the Fmoc-t-Bu-Trt protection ...
Brath, Ulrika   +2 more
core  

Cu Site Preference and Structural Evolution in Cu‐Doped BiMn7O12 Quadruple Perovskite

open access: yesAdvanced Physics Research, EarlyView.
Light Cu substitution in the quadruple perovskite BiMn7‐xCuxO12 progressively suppresses monoclinic distortion while enhancing local structural disorder and weakening magnetic order. Unexpected Cu site preferences inferred experimentally contrast with first‐principles predictions, revealing a delicate competition among local bonding, structural ...
Cheng Peng   +6 more
wiley   +1 more source

Four subtypes of disease-causing missense mutations underlie pathogenic protein interactions in neurodegenerative VPS13A disease

open access: yesThe Journal of Clinical Investigation
VPS13A is an intracellular lipid transfer protein comprising more than 3,000 amino acids. Mutations in human VPS13A cause VPS13A disease, a neurodegenerative disorder that affects movement and cognition.
Xing Lin   +6 more
doaj   +1 more source

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

open access: yesAnimal Research and One Health, EarlyView.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang   +10 more
wiley   +1 more source

Regulation of kinesin-2 motility by its β-hairpin motif. [PDF]

open access: yesNat Struct Mol Biol
Webb S   +4 more
europepmc   +1 more source

Recent Advances in Virus–Host Interactions, Antiviral Bioactive Compounds, and Breeding for Disease Resistance of Porcine Epidemic Diarrhea Virus

open access: yesAnimal Research and One Health, EarlyView.
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy