Ion-pairing interaction - Open Access .click

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Swapping the Positions in a Cross-Strand Lateral Ion-Pairing Interaction between Ammonium- and Carboxylate-Containing Residues in a β-Hairpin

Molecules, 2021
Cross-strand lateral ion-pairing interactions are important for antiparallel β-sheet stability. Statistical studies suggested that swapping the position of cross-strand lateral residues should not significantly affect the interaction.
Cheng-Hsin Huang +6 more
doaj +3 more sources

The Effects of Charged Amino Acid Side-Chain Length on Diagonal Cross-Strand Interactions between Carboxylate- and Ammonium-Containing Residues in a β-Hairpin

Molecules, 2022
The β-sheet is one of the common protein secondary structures, and the aberrant aggregation of β-sheets is implicated in various neurodegenerative diseases. Cross-strand interactions are an important determinant of β-sheet stability.
Jing-Yuan Chang +8 more
doaj +1 more source

Diagonal Interactions between Glutamate and Arginine Analogs with Varying Side-Chain Lengths in a β-Hairpin

Molecules, 2023
Cross-strand interactions are important for the stability of β-sheet structures. Accordingly, cross-strand diagonal interactions between glutamate and arginine analogs with varying side-chain lengths were studied in a series of β-hairpin peptides.
Nian-Zhi Li +5 more
doaj +1 more source

Advancements in the characterisation of oligonucleotides by high performance liquid chromatography‐mass spectrometry in 2021: A short review

Analytical Science Advances, 2022
The first oligonucleotide therapeutic was approved by the Food and Drug Administration in 1998, and since then, 12 nucleic acids have been commercialised as medicines.
Fabien Hannauer +5 more
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Separation of therapeutic oligonucleotides using ion-pair reversed-phase chromatography based on fundamental separation science

Journal of Chromatography Open, 2023
In recent decades, there has been a trend toward using larger biological molecules as new active pharmaceutical ingredients (APIs) instead of the classical small organic API molecules.
Torgny Fornstedt, Martin Enmark
doaj +1 more source

Design and optimization of metformin hydrophobic ion pairs for efficient encapsulation in polymeric drug carriers

Scientific Reports, 2022
Loading small molecular weight hydrophilic drugs into polymeric carriers is a challenging task. Metformin hydrochloride (MET) is a highly soluble oral antidiabetic drug of small size and high cationic charge.
Sara I. Abd-El Hafeez +3 more
doaj +1 more source

Stereosopecificity in [Co(sep)][Co(edta)]Cl₂·2H₂O

Chemistry, 2021
The X-ray structure of racemic [Co(sep)][Co(edta)]Cl2·2H2O is reported and reveals hetero-chiral stereospecificity in the interactions of [Co(sep)]3+ with [Co(edta)]−.
Peter Osvath, Allen Oliver, A. Graham Lappin +2 more
doaj +1 more source

Synthesis and characterizations of a novel composite films composed of polyethylene/oxide minerals

Next Materials, 2023
In this study, a new composite film consisting of polyethylene (PE)/oxide minerals (bentonite, silica, and diatomite) was successfully synthesized. Polymer modification was carried out by melting method.
Emine Kadioglu +5 more
doaj +1 more source

Synergistic effect of K+ and PANI in vanadium oxide hydration by interlayer engineering boosts the ammonium ion storage

SusMat, 2023
Aqueous ammonium‐ion (NH4+) hybrid supercapacitor (AA‐HSC), as a new type of energy storage device with great potential, is in the initial stage of rapid development.
Xingyu Chen +5 more
doaj +1 more source

Use of a Mixed Cationic-Reverse Phase Column for Analyzing Small Highly Polar Metabolic Markers in Biological Fluids for Multiclass LC-HRMS Method

Applied Sciences, 2020
The determination of small highly polar metabolites at low concentrations is challenging when reverse-phase (RP) chromatography is used for multiclass analysis.
Marco Roverso +4 more
doaj +1 more source

peptide
side-chain length
β-hairpin