Results 31 to 40 of about 26,663 (244)

Aggregation‐induced suppression of quantum tunneling by manipulating intermolecular arrangements of magnetic dipoles

Aggregate
The relaxation time under zero field reflects the memory retention capabilities of single‐molecule magnets (SMMs) when used as storage devices. Intermolecular magnetic dipole interaction is ubiquitous in aggregates of magnetic molecules and can greatly ...
Wei Deng, Shan‐Nan Du, Ze‐Yu Ruan, Xiao‐Jun Zhao, Yan‐Cong Chen, Jun‐Liang Liu, Ming‐Liang Tong   +6 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Bile Acids and Their Derivatives as Potential Modifiers of Drug Release and Pharmacokinetic Profiles

Frontiers in Pharmacology, 2018
Bile acids have received considerable interest in the drug delivery research due to their peculiar physicochemical properties and biocompatibility.
Nebojša Pavlović, Svetlana Goločorbin-Kon, Maja Ðanić, Bojan Stanimirov, Hani Al-Salami, Karmen Stankov, Momir Mikov   +6 more
doaj   +1 more source

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

FEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini, Freia S. Buus, Benjamin Schuler, Birthe B. Kragelund   +3 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Inclusion of MyAMI-derived Mg ∕ Ca corrections to the marine carbonate system in the cGENIE.cookie Earth system model (v.0.91) [PDF]

Geoscientific Model Development
The concentrations of the major cations (esp., Ca2+, Mg2+) in Earth's oceans have undergone large-scale fluctuations in the geological past. This is important because the key geochemical properties of the marine environment that underpin the global ...
M. Adloff, M. Adloff, T. M. Ganey, M. P. Hain, M. J. Henehan, S. E. Greene, A. Ridgwell   +6 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Ion pair interactions in noble metal complexes with halogen atoms [PDF]

Acta Crystallographica Section A Foundations and Advances, 2017
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Marchio', Luciano, Serpe, Angela, Deplano, Paola, Cuscusa, Mariangela   +3 more
openaire   +2 more sources