Results 181 to 190 of about 1,516,213 (305)
The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang +10 more
wiley +1 more source
Replica Exchange Molecular Dynamics Simulations on the Folding of Trpzip4 β-Hairpin [PDF]
Chenyi Liao, Zhou Jian
openalex +1 more source
5‐Methylcytosine Analysis of miRNAs in Minimal Change Disease
ABSTRACT Minimal change disease (MCD) is a glomerular disorder, which is the most common cause of nephrotic syndrome in children. Additionally, the prevalence of MCD in adults has been increasing in recent years. During protein synthesis, noncoding RNAs can be regulated through a variety of modifications, which helps preserve biological diversity and ...
Huiyi Zeng +14 more
wiley +1 more source
Catalytic Amyloids: Turning Fibrils Into Biocatalysts
Amyloids, traditionally associated with diseases, have emerged as versatile catalytic scaffolds. From natural amyloid sequences to bioinspired and de novo designs, we highlight strategies to construct catalytic active sites and anchor enzymes onto fibrils, creating versatile nanomaterials with tunable activities. ABSTRACT Amyloids have been regarded as
Alessandra Esposito +3 more
wiley +1 more source
Miniature β-Hairpin Mimetic by Intramolecular Hydrogen Bond and C-H···π Interactions. [PDF]
Nandi SK +4 more
europepmc +1 more source
Tyrosine Phosphorylation of the Well Packed EphrinB Cytoplasmic β-Hairpin for Reverse Signaling [PDF]
Jianxing Song
openalex +1 more source
Metal‐Directed Self‐Assembly in a Beta‐Sheet Miniprotein Scaffold
A rationally engineered miniprotein, V14C, which is based on the beta β‐sheet Foldon domain, self‐assembles via a metal‐binding site to form well‐defined oligomers in the presence of Zn2+, Hg2+, and Cd2+. This modular design expands the toolbox for creating custom metalloproteins, enabling studies of metal–protein interactions for biochemical functions
Chandan Muni Reddy +3 more
wiley +1 more source

