Results 171 to 180 of about 899,318 (275)

Effectiveness of Telehealth Low‐Carbohydrate Intervention in Preventing Chronic Kidney Disease: A Real‐World, Retrospective, Matched Cohort Study

Diabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 9054-9068, October 2026.
ABSTRACT Background Lifestyle interventions targeting metabolic health may influence chronic kidney disease (CKD) risk, particularly among adults with type 2 diabetes and obesity. We evaluated real‐world associations between a telehealth‐delivered, individualized nutrition therapy program (VINT) and CKD incidence and progression compared with usual ...
Shaminie J. Athinarayanan, Petter Bjornstad, Priya V. Shanmugam, Thomas Weimbs, Adam J. Wolfberg, Jeff S. Volek, Jonathan Himmelfarb, Richard J. Johnson   +7 more
wiley   +1 more source

β-Hydroxybutyrate-induced mitochondrial dysfunction and oxidative stress in BMSCs are ameliorated by mitophagy activation. [PDF]

Front Cell Dev Biol
Tang T, Zhou J, Jia X, Shao J, Wang M, Xia S, Chen S, Sun W, Wang J, Lai S.   +9 more
europepmc   +1 more source

α‐Hydroxybutyrate Association With Incident Type 2 Diabetes Over 10 Years Across Different Glycemic States

Diabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 9493-9504, October 2026.
ABSTRACT Aim To investigate the association between baseline plasma α‐hydroxybutyrate (α‐HB), an organic acid derived from aminoacid catabolism and glutathione anabolism, and the 10‐year incidence of Type 2 diabetes (T2DM). Materials and Methods This prospective study analysed 1349 participants from the Swedish PAROKRANK study.
Elena Fortin, Anna Norhammar, David Stadler, Peter L. Herzog, Giulia Ferrannini, Ele Ferrannini   +5 more
wiley   +1 more source

Sleep Improvement for Metabolic Health: A Feasibility Trial of a Digital Sleep Treatment in People With Insomnia and Non‐Diabetic Hyperglycaemia

Journal of Sleep Research, Volume 35, Issue 5, October 2026.
ABSTRACT Insomnia may play a causal role in type 2 diabetes (T2D). Addressing insomnia through cognitive behavioural therapy (CBTi) in people with non‐diabetic hyperglycaemia could potentially reduce the risk of progression to T2D. To inform a future randomised trial, we performed a feasibility study of digital CBT (dCBTi) in individuals at increased ...
Rachel Sharman, David Ray, Andrew Farmer, Poppy C. E. Green, Victoria Harris, Fredrik Karpe, Colin A. Espie, Diana Mantripp, Thomas Marjot, Niall M. McGowan, Jeremy W. Tomlinson, Simon D. Kyle   +11 more
wiley   +1 more source

β-hydroxybutyrate restores social deficits by suppressing HDAC9 in the ACC of Shank3B-deficient mice. [PDF]

EMBO Mol Med
Hu E, Li J, Qi C, Ge J, Li Y, Xue Q, Wu S, Wang W.   +7 more
europepmc   +1 more source

Designing PLA/PHBV Implants With Degradation Matched to Normal or Inflammatory Tissues

Journal of Applied Polymer Science, Volume 143, Issue 36, September 20, 2026.
PLA/PHBV blends are investigated under simulated normal and pathological conditions. Multivariate statistical analysis decouples the competing effects of water‐uptake‐driven hydrolysis and crystallinity‐imposed barriers. Melt‐state rheological parameters serve as structural probes linking phase morphology to degradation kinetics. A semi‐empirical model
Luyao Gao, Aleksey D. Drozdov, Yaqing Liu   +2 more
wiley   +1 more source

Systems Bioengineering of Septic Shock Metabolism: Citrulline, β-Hydroxybutyrate and Plasma Biomarker-Based Phenotyping. [PDF]

Biomolecules
Azamfirei L, Cehan VD, Cehan AR, Pui MC, Lazar A.   +4 more
europepmc   +1 more source

Low Carbohydrate Availability in Energy Balance Alters Bone Turnover and Muscle Proteomic Response With Limited Endocrine Disruption

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
Eight trained males completed 4 days of normal‐carbohydrate or low‐carbohydrate (81% reduction in carbohydrate) diets while maintaining energy balance and undertaking daily exercise. Low carbohydrate decreased total body water and fat‐free mass, increased circulating free fatty acids, glycerol and β‐hydroxybutyrate, alongside increased fat oxidation at
Erick Mosquera‐Lopez, Harry L. Taylor, Yusuke Nishimura, Carl Langan‐Evans, Sam O. Shepherd, Juliette A. Strauss, James P. Morton, Jatin G. Burniston, Jose L. Areta   +8 more
wiley   +1 more source

A review of capillary β-hydroxybutyrate cut-off levels for the exclusion and identification of diabetic ketoacidosis. [PDF]

J Diabetes Investig
Tran N, James S, Nash B, Gao F, Bennetts S, O'Neal D, Gaca M, Sher L, Ekinci EI.   +8 more
europepmc   +1 more source

Fenofibrate Protects Against Antipsychotic‐Induced Hyperglycemia Through Weight Loss and FGF21 Dependent Mechanisms

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
The proposed mechanism through which fenofibrate protects against olanzapine‐induced hyperglycemia in mice. ABSTRACT Antipsychotic (AP) medications, such as olanzapine, cause acute weight gain independent of hyperglycemia through a glucagon‐dependent mechanism.
Michael Akcan, Stewart Jeromson, Bradley J. Baranowski, Annalaura Bellucci, Serena Trang, Katelyn Eisner, Ailish Babicki‐Moore, Hadil Alfares, Meagan Arbeau, Kyle Medak, Margaret Hahn, David C. Wright   +11 more
wiley   +1 more source