Results 41 to 50 of about 899,318 (275)

BDH1‐mediated LRRC31 regulation dependent on histone lysine β‐hydroxybutyrylation to promote lung adenocarcinoma progression

MedComm, 2023
Lung adenocarcinoma (LUAD) is the most common form of lung cancer, with a consistently low 5‐year survival rate. Therefore, we aim to identify key genes involved in LUAD progression to pave the way for targeted therapies in the future.
Jingjing Huang, Lu Liang, Shiyao Jiang, Yueying Liu, Hua He, Xiaoyan Sun, Yi Li, Li Xie, Yongguang Tao, Li Cong, Yiqun Jiang   +10 more
doaj   +1 more source

Poly-β-hydroxybutyrate production by lactic acid bacteria [PDF]

FEMS Microbiology Letters, 1998
Poly-beta-hydroxybutyrate was determined in lactic acid bacteria belonging to the genera Lactobacillus, Lactococcus, Pediococcus and Streptococcus. Lactobacilli were grown in MRS broth, the others were grown in Elliker broth medium. Cell biomass was obtained by centrifugation. The cell walls were lysed with sodium hypochlorite.
Aslim, BELMA, Beyatli, Y, Caliskan, F, Gunduz, U   +3 more
openaire   +3 more sources

Broad‐Spectrum, Cell Envelope‐Active Marinocyclin Antibiotics From a Coral‐Derived Bacterium Are Effective Against Colistin‐Resistant Bacteria

Angewandte Chemie, EarlyView.
Marinocyclins, polycationic macrocyclic depsipeptides, were discovered by genome mining from the marine coral‐derived bacterium Aquimarina megaterium. The compounds have broad‐spectrum activity against gram‐positive and gram‐negative ESKAPE bacteria.
Clara Chepkirui, Sandra Silva, Jan Straetener, Chandrashekhar Padhi, Tina Keller‐Costa, Tess Lamer, Laura Reinke, Heike Brötz‐Oesterhelt, Rodrigo Costa, Jörn Piel   +9 more
wiley   +2 more sources

Safety of β‐hydroxybutyrate salts as a novel food pursuant to Regulation (EU) 2015/2283

EFSA Journal, 2022
Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on β‐hydroxybutyrate (BHB) salts as a novel food (NF) pursuant to Regulation (EU) 2015/2283.
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Dominique Turck, Torsten Bohn, Jacqueline Castenmiller, Stefaan De Henauw, Karen Ildico Hirsch‐Ernst, Alexandre Maciuk, Inge Mangelsdorf, Harry J McArdle, Androniki Naska, Carmen Pelaez, Kristina Pentieva, Alfonso Siani, Frank Thies, Sophia Tsabouri, Marco Vinceti, Francesco Cubadda, Thomas Frenzel, Marina Heinonen, Miguel Prieto Maradona, Rosangela Marchelli, Monika Neuhäuser‐Berthold, Morten Poulsen, Josef Rudolf Schlatter, Henk vanLoveren, Océane Albert, Tilemachos Goumperis, Helle Katrine Knutsen   +27 more
doaj   +1 more source

Factors affecting poly-β-hydroxybutyrate accumulation in cyanobacteria and in purple non-sulfur bacteria [PDF]

FEMS Microbiology Letters, 1992
Spirulina maxima and Rhodopseudomonas palustris, which are known to be capable of synthesizing poly-β-hydroxybutyrate (PHB), were grown under different conditions in order to investigate the metabolic significance of PHB synthesis in phototrophic microorganisms. The intracellular concentration of PHB in S.
DE PHILIPPIS, ROBERTO, A. ENA, M. GUASTINI, C. SILI, VINCENZINI, MASSIMO   +4 more
openaire   +1 more source

Consequences of reprogramming acetyl-CoA metabolism by 2,3,7,8-tetrachlorodibenzo-p-dioxin in the mouse liver

Scientific Reports, 2023
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a persistent environmental contaminant that induces the progression of steatosis to steatohepatitis with fibrosis in mice.
Giovan N. Cholico, Karina Orlowska, Russell R. Fling, Warren J. Sink, Nicholas A. Zacharewski, Kelly A. Fader, Rance Nault, Tim Zacharewski   +7 more
doaj   +1 more source

Exercise promotes the expression of brain derived neurotrophic factor (BDNF) through the action of the ketone body β-hydroxybutyrate

eLife, 2016
Exercise induces beneficial responses in the brain, which is accompanied by an increase in BDNF, a trophic factor associated with cognitive improvement and the alleviation of depression and anxiety. However, the exact mechanisms whereby physical exercise
Sama F Sleiman, Jeffrey Henry, Rami Al-Haddad, Lauretta El Hayek, Edwina Abou Haidar, Thomas Stringer, Devyani Ulja, Saravanan S Karuppagounder, Edward B Holson, Rajiv R Ratan, Ipe Ninan, Moses V Chao   +11 more
doaj   +1 more source

Ectopic Expression of the Rhizobium etli amtB Gene Affects the Symbiosome Differentiation Process and Nodule Development

Molecular Plant-Microbe Interactions, 1999
Under conditions of nitrogen limitation, soil bacteria of the genus Rhizobium are able to induce the development of symbiotic nodules on the roots of leguminous plants. During nodule organogenesis, bacteria are released endocytotically inside the invaded
Rosarita Taté, Michele Cermola, Anna Riccio, Maurizio Iaccarino, Mike Merrick, Reneé Favre, Eduardo J. Patriarca   +6 more
doaj   +1 more source

β-hydroxybutyrate as an Anti-Aging Metabolite

, 2021
The ketone bodies, especially β-hydroxybutyrate (β-HB), derive from fatty acid oxidation and alternatively serve as a fuel source for peripheral tissues including the brain, heart, and skeletal muscle.
Lian Wang, Peijie Chen, Weihua Xiao
core   +1 more source

Inhibition of adenosine 3′:5′-monophosphate accumulation in white fat cells by short chain fatty acids, lactate, and β-hydroxybutyrate

Journal of Lipid Research, 1976
The large increase in cyclic AMP accumulation by rat white fat cells seen in the presence of lipolytic agents plus methylxanthines and adenosine deaminase was markedly inhibited by lactate. However, lipolysis was unaffected by lactate.
J N Fain, R E Shephard
doaj   +1 more source