Results 61 to 70 of about 85,033 (176)

Effect of β-hydroxybutyrate acid on gene expression levels of antioxidant biomarkers and growth hormone–related genes in liver cell culture

Journal of Veterinary Research
In dairy cattle, oxidative stress is a predominant problem associated with diseases and reproductive health issues. This study aimed to detect the variation in the antioxidant biomarkers by adding different concentrations of β-hydroxybutyric acid (BHBA ...
Mohsin Muhammad Ali, Zhou Xiaojing, Huiru Yu, Shen Wenxiang, He Baoxiang, Sobiech Przemysław, Pierzchała Mariusz, Ogłuszka Magdalena, Starzyński Rafał, Kalra Garima, Deshmukh Bharti, Thangarasu Revathy, Kashyap Neeraj, Czarnik Urszula, Lepczyński Adam, Woźniakowski Grzegorz, Pareek Chandra S.   +16 more
doaj   +1 more source

Efficacy evaluation of a commercially available MCT enriched therapeutic diet on dogs with idiopathic epilepsy treated with zonisamide: a prospective, randomized, double-blinded, placebo-controlled, crossover dietary preliminary study

BMC Veterinary Research, 2023
Background Idiopathic epilepsy (IE) is a common, chronic brain dysfunction in dogs. Recently, the effect of feeding a diet enriched with medium-chain triglycerides (MCTs) on seizure frequency has been evaluated in several studies in dogs with IE. However,
Kazumasa Nakatsuka, Brian Zanghi, Daisuke Hasegawa   +2 more
doaj   +1 more source

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

The Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor, Nycolle I. S. Souza, Bruno G. Anjos, Stephen G. Matthews, Enrrico Bloise   +4 more
wiley   +1 more source

Seleção de linhagens de Bacillus produtoras de polihidroxialcanoatos a partir de resíduo do processamento de mandioca [PDF]

, 2009
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia de Alimentos.Frente aos problemas ocasionados pelo uso dos plásticos de origem petroquímica, surgiu a necessidade de se buscarem ...
Krueger, Cristhiane Leite
core  

Metabolic Assessment in Human Pluripotent Stem Cell‐Derived Cerebral Organoids Using HR‐MAS NMR Spectroscopy

NMR in Biomedicine, Volume 39, Issue 8, August 2026.
We present a direct method for evaluating metabolism in intact hPSC‐derived cerebral organoids (COs) via HR‐MAS 1H‐NMR spectroscopy. This approach suggests that COs exhibit a metabolic profile similar to in vivo human fetal brain, with high levels of lactate and hTau, low levels of NAA, and equimolar levels of Glu and Gln.
Maria Alejandra Castilla Bolanos, Vorapin Chinchalongporn, Rajshree Ghosh Biswas, Colleen Bailey, Maggie Wu, Ronald Soong, Fermisk Saleh, Andre Simpson, Carol Schuurmans, Jamie Near   +9 more
wiley   +1 more source

DADA improves blood glucose, lactate, β-hydroxybutyric acid, free fatty acids and ATP levels.

, 2014
Mice infected with 120 and 200 pfu of IAV were treated with oral DADA at 50 mg/kg or vehicle at 12-h intervals and the levels of glucose, lactate, free fatty acids, β-hydroxybutyric acid, and ATP in the blood were analyzed at day 7 post-infection. Values
Yoshikazu Yamamoto (568798), Masaaki Hanawa (568799), Irene L. Indalao (568797), Hiroshi Kido (369311), Kazuhiko Yamane (399857), Junji Chida (399855)   +5 more
core   +1 more source

Long‐Term Follow‐Up of Patients With Mitochondrial Carbonic Anhydrase VA Deficiency. A Case Report and Literature Review

JIMD Reports, Volume 67, Issue 4, July 2026.
ABSTRACT Mitochondrial carbonic anhydrase VA (CA‐VA) deficiency is a rare inherited metabolic disorder caused by biallelic variants of the CA5A gene. It presents with hyperammonemia, lactic acidosis, and ketonuria, with or without hypoglycemia. We report the long‐term follow‐up of the first two reported cases of CA‐VA deficiency: a 16‐year‐old female ...
Shaymaa Shurrab, Amira Mobarak, Gabriella Horvath, Sylvia Stocker‐Ipsiroglu, Clara van Karnebeek, Ramona Salvarinova‐Zivkovic   +5 more
wiley   +1 more source

Produção de polihidroxialcanoatos por Cupriavidus necator, em batelada sequencial com reciclo externo de células, e modelagem do processo a partir da análise de fluxos metabólicos [PDF]

, 2015
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia de Alimentos, Florianópolis, 2015.Os Polihidroxialcanoatos (PHAs), com destaque para o Poli(3-hidroxibutirato) (P(3HB)) e o Poli(3 ...
Schmidt, Mélodi
core  

Targeting Mitochondria in Aging‐Related Diseases: Therapeutic Potential and Obstacles

MedComm, Volume 7, Issue 6, June 2026.
This article systematically summarized the specific mechanism of aging‐related diseases caused by mitochondrial dysfunction, and summarized the broad‐spectrum treatment methods and disease targeted treatment strategies for mitochondria. At the same time, it also pointed out the dilemma faced by mitochondrial targeted treatment.
Zijie Xiang, Yu Chen, Xishui Liu, Haowen Lu, Yuqing Yang, Lei Xing, Yu Zhang, Chuandong Lang, Siming Zhang, Shixiang Zhao, Youzhi Hong, Jiaxiang Bai, Yusen Qiao   +12 more
wiley   +1 more source

Gamma-hydroxybutyric acid and growth hormone secretion: Studies in rats and dogs

, 2000
Gamma-hydroxybutyric acid, a gamma-aminobutyric acid metabolite, and baclofen, a gamma-aminobutyric acid B agonist, are endowed with a small growth hormone-releasing activity in human beings.
A.E. Rigamonti, E. E. Müller
core   +1 more source