Results 71 to 80 of about 85,033 (176)

Solvent‐Dependent Biological Activities of Aqueous and Ethanolic Extracts From Edible Insect Larvae

open access: yesFood Science &Nutrition, Volume 14, Issue 5, May 2026.
This study compares the functional activity profiles of aqueous and ethanolic extracts from edible insect larvae. Solvent‐dependent extraction resulted in distinct bioactivity patterns, highlighting the importance of extraction conditions in determining the functional potential of insect‐derived bioactive compounds.
Min‐Cheol Kang   +9 more
wiley   +1 more source

Comparison of serum biochemical parameters in ketotic and healthy Siirt Colored Mohair goats during early lactation to identify potential Biomarkers of lactation ketosis

open access: yesRevista Científica
This study aimed to compare serum biochemical parameters between ketotic and healthy Siirt colored mohair goats during early lactation, to diagnose subclinical lactation ketosis and identify potential biomarkers.
Mehmet Irmak   +8 more
doaj   +1 more source

Antennaria dioica (L.) Gaertn. (Asteraceae): From Metabolite Profiling to Comprehensive Evaluation of In Vitro and In Silico Enzyme Inhibitory Activity

open access: yesFood Science &Nutrition, Volume 14, Issue 5, May 2026.
Antennaria dioica (L.) Gaertn. is a perennial herb from the tribe Gnaphalieae of the Asteraceae family. In‐depth phytochemical profiling and in vitro antioxidant and enzyme inhibition assessment of methanol‐aqueous extract from the A. dioica aerial parts were integrated with molecular docking study.
Dimitrina Zheleva‐Dimitrova   +7 more
wiley   +1 more source

1H-NMR-based metabonomic studies on the anti-depressant effect of genipin in the chronic unpredictable mild stress rat model. [PDF]

open access: yesPLoS ONE, 2013
The purpose of this work was to investigate the anti-depressant effect of genipin and its mechanisms using (1)H-NMR spectroscopy and multivariate data analysis on a chronic unpredictable mild stress (CUMS) rat model.
Jun-Sheng Tian   +5 more
doaj   +1 more source

Polyhydroxyalkanoates as Sustainable Agricultural Plastics: Processing Strategies, Performance, and Environmental Perspectives

open access: yesMacromolecular Materials and Engineering, Volume 311, Issue 5, May 2026.
This review highlights polyhydroxyalkanoates (PHAs) as biodegradable materials for agricultural plastics. It outlines how composition, processing, and formulation strategies shape material properties and end‐of‐life behavior. Applications in films and foams are discussed alongside current limitations in cost and scalability, emphasizing emerging ...
Giulia de Simão de Sousa   +4 more
wiley   +1 more source

β-Hydroxybutyrate promotes chemoresistance and proliferation in breast cancer cells

open access: yesBiochemistry and Biophysics Reports
Breast cancer is the most prevalent cancer among women, posing significant challenges due to its heterogeneity. Recent studies suggest that the ketogenic diet (KD) may enhance chemotherapy efficacy by modulating cancer cell metabolism, particularly ...
Milad Mashinchian   +3 more
doaj   +1 more source

Comorbid Alzheimer's Disease and Type 2 Diabetes Microbiota Shape Age‐Associated Gut–Brain Axis Profiles

open access: yesAging Cell, Volume 25, Issue 5, May 2026.
Fecal microbiota transplantation from elderly donors with Alzheimer's disease, type 2 diabetes, or both conditions into antibiotic‐treated mice revealed that comorbid microbiota produce the most severe dysbiosis and strongest suppression of hippocampal neurotrophic gene expression.
Alessandro Atzeni   +16 more
wiley   +1 more source

Profiling of HCAR1 signalling reveals Gαi/o and Gαs activation without β‐arrestin recruitment and the discovery of an allosteric agonist

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 10, Page 2219-2235, May 2026.
Abstract Background and Purpose Lactate, historically viewed as a metabolic by‐product, has emerged as a signalling molecule via the G protein–coupled receptor Hydroxycarboxylic Acid Receptor 1 (HCAR1). The receptor is primarily expressed in adipocytes but also found in various other tissues.
Simon Lind   +6 more
wiley   +1 more source

Acid-Controlled Access to β‑Sulfenyl Ketones and α,β-Disulfonyl Ketones by Pummerer Reaction of β‑Keto Sulfones and Sulfoxides

open access: yes, 2019
A convenient acid-mediated reaction of β-keto sulfones with sulfoxides under metal-free conditions has been developed, thereby delivering the acid-controlled synthesis of β-sulfenyl ketones and α,β-disulfonyl ketones in good to excellent yields.
Meihua Xie (1628227)   +9 more
core   +2 more sources

SALT TOLERANCE AND PHB PRODUCTION OF Rhizobium FRANK ISOLATES OF ROOT NODULES OF WILD Vicia aintabensis BOISS. HAUSSKN. EX BOISS

open access: yesTrakya University Journal of Natural Sciences, 2017
This study was performed in order to determine the tolerance of Rhizobium Frank isolates obtained from root nodules of wild Vicia aintabensis Boiss. amp; Hausskn. ex Boiss to different NaCl concentrations (0, 100, 150, 200, 250, 300, 350, 400 and 450mM)
Çiğdem Küçük
doaj   +1 more source

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