Results 221 to 230 of about 764,478 (294)

Peptidoglycan recycling is critical for cell division, cell wall integrity, and β-lactam resistance in <i>Caulobacter crescentus</i>. [PDF]

Elife
Richter P, Merz A, Biboy J, Paczia N, Glatter T, Ng J, Vollmer W, Thanbichler M.   +7 more
europepmc   +1 more source

Whole Genome Characterization of Klebsiella Strains in European Hedgehogs and Human Nosocomial Settings Identified Shared Sequence Types, Antimicrobial Resistance Genes and Plasmids

Zoonoses and Public Health, EarlyView.
ABSTRACT Introduction Klebsiella pneumoniae is a pathogen associated with healthcare‐acquired infections and antimicrobial resistance (AMR) to beta‐lactams and carbapenems. Although wild animals are not typically exposed to antibiotics, they can harbour resistant strains. The European hedgehog (Erinaceus europaeus) is increasingly found in urban areas,
Biel Garcias, Chiara Seminati, Carolin M. Kobras, Samuel K. Sheppard, Rafael A. Molina‐López, Laila Darwich   +5 more
wiley   +1 more source

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

The Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor, Nycolle I. S. Souza, Bruno G. Anjos, Stephen G. Matthews, Enrrico Bloise   +4 more
wiley   +1 more source

Gingival enlargement and dentition loss associated with disseminated Cryptococcus neoformans infection in a dog

Veterinary Record Case Reports, Volume 14, Issue 3, August 2026.
Abstract A 1‐year‐old, female, spayed, mixed‐breed dog was examined by a referring veterinarian for a 1‐week history of sneezing, bilateral mucoid nasal discharge, mild bilateral ocular discharge and stertor. During rhinoscopy, a plant awn foreign body was removed, but upper respiratory signs persisted. Computed tomography of the head revealed findings
Glynn Woods, Allison Volk, Janny Evenhuis, Abbie Metcalfe, Jane E. Sykes   +4 more
wiley   +1 more source

Selection of porin and LPS mutants during infection by phage T4 facilitates the emergence of β-lactam resistance in Escherichia coli. [PDF]

NPJ Antimicrob Resist
Le-Boulch J, Charneau E, Chevallereau A, Gutierrez A.   +3 more
europepmc   +1 more source

Chiral (Stereoselective) Drugs, Asymmetric Synthesis, and Racemic Resolution Methods

Chirality, Volume 38, Issue 7, July 2026.
Chirality is crucial in drug development since both biological targets in the organism and the majority of pharmaceutical compounds are chiral. The synthesis and resolution of chiral compounds are critical steps while developing chiral drugs. Asymmetric synthesis and racemic resolution are the two most common methods for obtaining enantiopure drugs ...
Burcu Karayavuz, Cigdem Karaaslan Kirmizioglu   +1 more
wiley   +1 more source

Antimicrobial resistance in wildlife: detection of β-lactam/carbapenem resistance genes in European hedgehogs (Erinaceus europaeus, Linnaeus 1758) in Italy. [PDF]

Vet Res Commun
Di Francesco A, Salvatore D, Bertelloni F, Ceccherelli R, Lupini C, Ebani VV.   +5 more
europepmc   +1 more source

Tissue and Serum Concentrations of Time‐Dependent Antibiotics in Infected Diabetic Foot Ulcers by Bolus or Continuous Administration: The Randomised DFIATIM Trial

Diabetes/Metabolism Research and Reviews, Volume 42, Issue 5, July 2026.
ABSTRACT Aims The clinical effectiveness of antibiotic (ATB) therapy in patients with infected diabetic foot ulcers (iDFUs) depends on achieving sufficient ATB concentrations in both serum and peripheral tissues. This study evaluated the availability and bactericidal activity of the time‐dependent ATBs—ceftazidime (CTZ) and amoxicillin/clavulanate (AMC)
Radka Jarošíková, Dominika Sojáková, Simona Antalová, Petr Tůma, Jan Polák, Michal Dubský, Andrea Němcová, Veronika Wosková, Pavol Beca, Istvan Modos, Jan Mareš, Jakub Mrázek, Chahrazed Mekadim, Markéta Skružná, Vladimíra Fejfarová   +14 more
wiley   +1 more source

In vitro efficacy of sulbactam/durlobactam combined with β-lactam antibiotics in Australian Mycobacterium abscessus isolates. [PDF]

J Antimicrob Chemother
Patterson-Fahy K, Carter R, Bell SC, Evans IES, Burke AJ, Thomson RM.   +5 more
europepmc   +1 more source

Fluorinative Olefin Bond Functionalization of Selected Functionalized Cycloalkenes

Israel Journal of Chemistry, Volume 66, Issue 4, July 2026.
Palladium‐catalyzed ring olefin bond difunctionalization, through functional group and substrate‐dependent arylfluorination, of selected functionalized cycloalkenes has been studied. Palladium‐catalyzed ring olefin bond difunctionalization through arylfluorination of selected five‐, six‐, and seven‐membered functionalized cycloalkenes has been studied.
Tamás T. Novák, Tamás Holczbauer, Máté Sulyok‐Eiler, Pál T. Szabó, Melinda Nonn, Gábor Turczel, Anas Semghouli, Santos Fustero, Jianlin Han, Gábor Hornyánszky, Loránd Kiss   +10 more
wiley   +1 more source