Results 241 to 250 of about 937,622 (274)

Maternal nutrition as a key determinant of placental and developing blood–brain barrier xenobiotic protective functions

The Journal of Physiology, EarlyView.
Abstract figure legend Suboptimal maternal nutrition alters placental and developing blood–brain barrier (BBB) protective function and is associated with increased fetal brain vulnerability. In the placenta, nutritional adversity may reduce the exchange surface area and promote meta‐inflammation, compromising barrier efficiency in a model‐ and context ...
Kristin L. Connor, Nycolle I. S. Souza, Bruno G. Anjos, Stephen G. Matthews, Enrrico Bloise   +4 more
wiley   +1 more source

Differential risk signals of cutaneous adverse drug reactions among β-lactam antibiotics: ceftriaxone shows increased signals for SJS/TEN in clinical and real-world cohorts. [PDF]

Front Med (Lausanne)
von Grundherr L, Faesser HA, Recke A, Ludwig RJ, Boch K, Curman P.   +5 more
europepmc   +1 more source

Nacubactam: a review on mechanistic insights and therapeutic promise for combating β-lactam resistance among multidrug-resistant Gram-negative pathogens. [PDF]

Ann Med Surg (Lond)
Kumar D, Kaur N, Surender, Aman S, Bibi A.   +4 more
europepmc   +1 more source

Phage-antibiotic synergy restores β-lactam efficacy in MDR Klebsiella quasipneumoniae biofilms and suppresses resistance. [PDF]

J Biomed Sci
Tchatchiashvili T, Marquet M, Gabashvili E, Mirza KA, Lohde M, Brandt C, Ehricht R, Pletz MW, Makarewicz O.   +8 more
europepmc   +1 more source

Peptidoglycan recycling is critical for cell division, cell wall integrity, and β-lactam resistance in <i>Caulobacter crescentus</i>. [PDF]

Elife
Richter P, Merz A, Biboy J, Paczia N, Glatter T, Ng J, Vollmer W, Thanbichler M.   +7 more
europepmc   +1 more source

Acute Pustular Facial Eruption in a 5‐Year‐Old Boy

Pediatric Dermatology, EarlyView.
Naia Oillarburu, Magalie Coco‐Viloin, Emilie Tournier, Juliette Mazereeuw‐Hautier, Maella Severino‐Freire   +4 more
wiley   +1 more source

Unraveling the mechanisms behind the enhanced efficacy of β-lactam-based sideromycins. [PDF]

Commun Biol
Lacasse E, Binette R, Guibout H, Liu R, Lin YM, Ghosh M, Boudreault PL, Miller MJ, Malouin F.   +8 more
europepmc   +1 more source

Simultaneous measurement of piperacillin, tazobactam and meropenem in patient samples using LC-MS/MS to support β-lactam therapeutic drug monitoring.

Anal Methods
Federico S, Williams S, Wilson RC, Arkel P, Gilchrist MJ, Holmes AH, Rawson TM, Riezk A.   +7 more
europepmc   +1 more source

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Diazoketones as precursors in β-lactam synthesis. New insights into the mechanism of the photochemically induced Staudinger reaction

Journal of the Chemical Society, Perkin Transactions 1, 2001
Diazoketones 1–3, derived from suitably protected amino acids (Ala, Val and Tle), have been photochemically rearranged in the presence of imines leading exclusively to trans-arranged 4-aryl- and cinnamoyl-substituted β-lactams 17–33 with up to 84% yield. Selectivities were dependent on the steric demand of the amino acid side-chain ranging from 65 ∶ 35
Michael R. Linder, Wolfgang U. Frey, Joachim Podlech   +2 more
openaire   +1 more source