Journal of Immunology Research, 2022 Introduction. The risk of extended spectrum β-lactamase (ESBL) bacterial acquisition in patients with β-lactam allergy has been poorly investigated. In a previous study conducted over a 6-year long period (2007-2012), we found that patients with declared
Alessio Strazzulla +9 more
doaj +1 more source
The barrier function of the outer membrane ofPseudomonas maltophiliain the diffusion of saccharides and β-lactam antibiotics [PDF]
FEMS Microbiology Letters, 1989 This paper reports that the efficiency of solute diffusion through the outer membrane of Pseudomonas maltophilia is roughly 3 to 5% of that of Escherichia coli. This is despite the fact that the outer membrane pore(s) is only a little smaller than that of E. coli. These results suggest that P. maltophilia has a low copy number of porin(s).
E, Yamazaki, J, Ishii, K, Sato, T, Nakae
openaire +2 more sources
, 2019 Background: Combining aminoglycosides with β-lactam antibiotics for treating serious infections has not been associated with reduced mortality in previous meta-analyses.
Roberts, Prof Jason +8 more
core +1 more source
β-Lactam induction of ISEcp1B-mediated mobilization of the naturally occurringblaCTX-Mβ-lactamase gene ofKluyvera ascorbata [PDF]
FEMS Microbiology Letters, 2008 ISEcp1B is an insertion element associated with the emerging expanded-spectrum beta-lactamase bla(CTX-M) genes in Enterobacteriaceae. Because ISEcp1B-bla(CTX-M)positive strains may be identified from humans and animals, the ability of this insertion sequence to mobilize the bla(CTX-M-2) gene was tested from its progenitor Kluyvera ascorbata to study ...
Nordmann, Patrice +2 more
openaire +3 more sources
Imide and isatin derivatives as β-lactam mimics of β-lactam antibiotics
, 2002 Activated γ-lactams, which are derivatives of succinimide, phthalimide and isatin with suitable elements of molecular recognition, have been synthesised as mimics of the ß-lactam antibiotics and their chemical and biological reactivity ...
Ronald H.B. Galt +10 more
core +1 more source
Fluoroquinolones versus β-Lactam/β-Lactamase Inhibitors in Outpatients with Chronic Obstructive Pulmonary Disease and Pneumonia: A Nationwide Population-Based Study. [PDF]
PLoS ONE, 2015 Studies on the association between antibiotic treatment and outcomes in outpatients with chronic obstructive pulmonary disease (COPD) and pneumonia are scarce.
Kuan-Yin Lin +4 more
doaj +1 more source
Commonly prescribed β-lactam antibiotics induce C. trachomatis persistence/stress in culture at physiologically relevant concentrations [PDF]
Frontiers in Cellular and Infection Microbiology, 2014 Chlamydia trachomatis, the most common bacterial sexually transmitted disease agent worldwide, enters a viable, non-dividing and non-infectious state (historically termed persistence and more recently referred to as the chlamydial stress response) when exposed to penicillin G in culture.
Kintner, Jennifer +4 more
openaire +4 more sources
A Concise Asymmetric Synthesis of A β-Lactam-Based Cholesterol Absorption Inhibitor
, 2016 A concise, four-step, asymmetric synthesis of a β-lactam-based cholesterol absorption inhibitor, Sch 57939, was developed. The discovery of a one-step enantio- and diastereoselective synthesis of a trans-β-lactam provided easy access to the desired ...
George Guangzhong Wu (3075429)
core +1 more source
Emerging Microbes and InfectionsSince β-lactam antibiotics are widely used, emergence of bacteria with resistance to them poses a significant threat to society. In particular, acquisition of genes encoding β-lactamase, an enzyme that degrades β-lactam antibiotics, has been a major ...
Hyunhee Kim +5 more
doaj +1 more source
β-Lactam-Based Azomethine Ylide Reactivity. Expedient Synthesis of Carbapenams and Carbapenems
, 2016 β-Lactam-Based Azomethine Ylide Reactivity.
Timothy Gallagher (1261572) +6 more
core +1 more source