Results 41 to 50 of about 697,712 (159)

P2Y6 receptors are involved in mediating the effect of inactivated avian influenza virus H5N1 on IL-6 & CXCL8 mRNA expression in respiratory epithelium. [PDF]

PLoS ONE, 2017
One of the key pathophysiologies of H5N1 infection is excessive proinflammatory cytokine response (cytokine storm) characterized by increases in IFN-β, TNF-α, IL-6, CXCL10, CCL4, CCL2 and CCL5 in the respiratory tract.
Nawiya Huipao, Suparerk Borwornpinyo, Suwimon Wiboon-Ut, Craig R Campbell, Il-Ha Lee, Siriphun Hiranyachattada, Chonlaphat Sukasem, Arunee Thitithanyanont, Chumpol Pholpramool, David I Cook, Anuwat Dinudom   +10 more
doaj   +1 more source

Cross-species chimeras reveal BamA POTRA and β-barrel domains must be fine-tuned for efficient OMP insertion [PDF]

, 2015
BAM is a conserved molecular machine, the central component of which is BamA. Orthologues of BamA are found in all Gram-negative bacteria, chloroplasts and mitochondria where it is required for the folding and insertion of β-barrel containing integral ...
Jeeves, Mark, Mason, Jessica L, Knowles, Timothy J., Rossiter, Amanda E, Rossiter, Amanda E.; id_orcid, Browning, Douglas F., Bavro, Vassiliy N., Henderson, Ian R., Cunningham, Adam F., Overduin, Michael, Sevastsyanovich, Yanina R., Rossiter, Amanda E., Donald, James W., Browning, Douglas F, Wells, Timothy J, Henderson, Ian R, Knowles, Timothy J.; id_orcid, Wells, Timothy J., Palmer, Tracy, Knowles, Timothy J, Sevastsyanovich, Yanina R, Cunningham, Adam F, Mason, Jessica L., Bavro, Vassiliy N, Donald, James W   +24 more
core   +1 more source

Development of a next-generation chikungunya virus vaccine based on the HydroVax platform.

PLoS Pathogens, 2022
Chikungunya virus (CHIKV) is an emerging/re-emerging mosquito-borne pathogen responsible for explosive epidemics of febrile illness characterized by debilitating polyarthralgia and the risk of lethal infection among the most severe cases.
Dawn K Slifka, Hans-Peter Raué, Whitney C Weber, Takeshi F Andoh, Craig N Kreklywich, Victor R DeFilippis, Daniel N Streblow, Mark K Slifka, Ian J Amanna   +8 more
doaj   +1 more source

A genome wide association scan for (1,3;1,4)-β-glucan content in the grain of contemporary 2-row Spring and Winter barleys [PDF]

, 2014
Background: (1,3;1,4)-β-Glucan is an important component of the cell walls of barley grain as it affects processability during the production of alcoholic beverages and has significant human health benefits when consumed aboverecommended threshold levels.
Russell, J., Oakey, H., Neil Shirley, Jennifer M Washington, Schreiber, Miriam, Booth, A., Joanne Russell, Russell, Joanne, Houston, Kelly, Houston, K., Fincher, G., Booth, Allan, Helena Oakey, Schreiber, M., Shirley, Neil, Shirley, N., Washington, Jennifer M., Rachel A Burton, Halpin, C., Burton, Rachel A., Waugh, R., Miriam Schreiber, Halpin, Claire, Robbie Waugh, Oakey, Helena, Fincher, Geoffrey B., Washington, J., Kelly Houston, Geoffrey B Fincher, Allan Booth, Waugh, Robbie; id_orcid, Burton, R., Claire Halpin   +32 more
core   +1 more source

Real-time PCR assay development for the control of vaccine against hemorrhagic fever with renal syndrome

Вопросы вирусологии, 2021
Introduction. Hemorrhagic fever with renal syndrome (HFRS) holds a leading place among natural focal human diseases in Russian Federation. There is no etiotropic therapy for the disease now. The vaccine prophylaxis is the most effective method to control
M. S. Egorova, S. S. Kurashova, A. A. Ishmukhametov, M. V. Balovneva, A. A. Deviatkin, M. V. Safonova, S. V. Ozherelkov, Yu. Kh. Khapchaev, A. S. Balkina, A. V. Belyakova, T. K. Dzagurova, E A. Tkachenko   +11 more
doaj   +1 more source

Cytoplasmic PML promotes TGF-β-associated epithelial–mesenchymal transition and invasion in prostate cancer [PDF]

, 2016
Epithelial–mesenchymal transition (EMT) is a key event that is involved in the invasion and dissemination of cancer cells. Although typically considered as having tumour-suppressive properties, transforming growth factor (TGF)-β signalling is altered ...
Powe, DG, Buczek, ME, Hulman, J, R Parkinson, Hulman, G, Van Schalkwyk, G, Pockley, AG, T Regad, Regad, T, C Johnson, Rees, RC, A G Pockley, M E Buczek, Miles, AK, A K Miles, R C Rees, D G Powe, W Green, D J Boocock, G Hulman, J Hulman, Johnson, C, Parkinson, R, Green, W, G van Schalkwyk, Boocock, DJ   +25 more
core   +1 more source

Stabilisation du lait par addition de Bêta-propiolactone [PDF]

, 1974
See PDF file of the article.Vaya al archivo pdf del artí­culo.L\u27addition de 0,5 p. 1 000 Bêta-propiolactone au lait permet de le conserver durant au moins 48 heures de plus qu\u27un lait témoin non traité.
Blancou, Jean
core   +7 more sources

Evaluation of the effectiveness of chemical inactivation and immunogenicity of the Omicron variant of the SARS-CoV-2 virus

Вопросы вирусологии
Introduction. The rapid spread of coronavirus infection COVID-19 among the population of many countries around the world has contributed to the emergence of many genetic variants of SARS-CoV-2.
Gulzhan A. Zhapparova, Balzhan S. Myrzakhmetova, Talshyngul M. Tlenchiyeva, Aiganym A. Tussipova, Karina B. Bissenbayeva, Aizhan S. Toytanova, Lespek B. Kutumbetov   +6 more
doaj   +1 more source

Inactivation of Wild Poliovirus with β-Propiolactone

Vaccines
Objectives: Antiviral vaccines are usually created by inactivating viruses using physical or chemical methods. Inactivation of poliovirus with β-propiolactone (BPL) has advantages, including the absence of a requirement for long-term incubation with the ...
Anastasia Kovpak, Sergey Pashkov, Mariia Kostrova, Kirill Nebesnyi, Nikita Yakovlev, Olga Polyakova, Vladislav Vasilenko, Lycheva Natalia, Yury Ivin, Anastasia Piniaeva, Alexandra Siniugina, Aydar Ishmukhametov   +11 more
doaj   +1 more source

Synthesis of Poly(2-methyl-3-hydroxyoctanoate) via Anionic Polymerization of α-Methyl-β-pentyl-β-propiolactone [PDF]

, 2001
Synthesis of an alpha,beta-alkyl branched polyester, i.e., poly(2-methyl-3-hydroxyoctanoate), has been accomplished via anionic polymerization of alpha-methyl-beta-pentyl-beta-propiolactone mediated by supramolecular complexes of potassium methoxide or ...
Jedlinski, Z, Kowalczuk, M, Lenz, RW, Hazer, B, Arkin, AH, Adamus, G   +5 more
core   +1 more source