Human pancreatic microenvironment promotes β-cell differentiation via non-canonical WNT5A/JNK and BMP signaling [PDF]
, 2022 Jolanta Chmielowiec +8 more
openalex +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Modified Non-Linear Triangular Neutrosophic Numbers: Theory and Applications in Integral Equation [PDF]
Neutrosophic Sets and SystemsExisting methods for handling uncertainty and imprecision often fall short in addressing complex real-world problems. To overcome these limitations, this paper introduces a novel Generalized Non-Linear Triangular Neutrosophic Number (GNLTNN) that ...
Mohammed Shapique, E. Mathivadhana
doaj +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Horticultural Science, 2007 The aim of this study was to analyze both the morphological and chemical characteristics of Acorus calamus plants collected from the natural sites in the Czech Republic and to compare them to the sweet flags growing in Finland, Slovenia and Canada, which
K. Dušek +4 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
A Review of Pharmacology, Toxicity and Pharmacokinetics of 2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-Glucoside [PDF]
, 2022 Cheng Wang +7 more
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FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
SPECT-OPT multimodal imaging enables accurate evaluation of radiotracers for β-cell mass assessments [PDF]
, 2016 Wael A. Eter +7 more
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Retinal Delivery of the Protein Kinase C-β Inhibitor Ruboxistaurin Using Non-Invasive Nanoparticles of Polyamidoamine Dendrimers [PDF]
, 2022 Rehab A. Alshammari +10 more
openalex +1 more source