Results 201 to 210 of about 145,582 (253)

N-cadherin and β1 integrin coordinately regulate growth plate cartilage architecture. [PDF]

Mol Biol Cell
Greer SE, Haller SJ, Lee D, Dudley AT.
europepmc   +1 more source

PABPC1 in Cancer: From a Translational Housekeeper to a Stress‐Responsive Regulatory Hub

Cancer Science, EarlyView.
PABPC1 shifts from a translational housekeeper to a stress‐responsive oncogenic hub via phase separation, PTMs, and non‐coding RNA crosstalk, selectively driving oncogene translation and therapy resistance in cancer. ABSTRACT PABPC1, long recognized as a constitutive translational housekeeper, has emerged as a stress‐responsive translational ...
Cuiwei Zhang, Ye Zhu, Wenbo Long
wiley   +1 more source

β1 integrin mediates unresponsiveness to PI3Kα inhibition for radiochemosensitization of 3D HNSCC models. [PDF]

Biomed Pharmacother
Korovina I, Elser M, Borodins O, Seifert M, Willers H, Cordes N.   +5 more
europepmc   +1 more source

Defining the role of αC helix interactions in the activation of the integrin αI domain

The FEBS Journal, EarlyView.
The α2I domain of the α2β1 integrin contains a distinctive αC helix and a conserved Arg288‐Glu318 ion pair that stabilizes the closed state of the domain. Disruption of this ion pair in the activated α2I variant unwinds the αC helix, which allows interaction with additional collagen‐binding sites increasing collagen binding.
Liisa Pösö, Tomi T. Airenne, Jarmo Käpylä, Hongmin Tu, Eva Bligt‐Lindén, Vimal Parkash, Jyrki Heino, Tiina A. Salminen   +7 more
wiley   +1 more source

ADAM12-Generated Basigin Ectodomain Binds β1 Integrin and Enhances the Expression of Cancer-Related Extracellular Matrix Proteins. [PDF]

Int J Mol Sci
Mygind KJ, Nikodemus D, Gnosa S, Kweder R, Albrechtsen NJW, Kveiborg M, Erler JT, Albrechtsen R.   +7 more
europepmc   +1 more source

CD36‐mediated lipid rewiring in the metabolic adaptation of tumour ecosystems

The FEBS Journal, EarlyView.
Nutrient deprivation drives a lipid‐centric shift in tumour metabolic symbiosis and signalling network. CD36 functions as a bidirectional bridge, transferring fatty acids from stromal donors (adipocytes, CAFs) to the ecosystem tumour‐ and microenvironment‐dependently.
Anna Sebestyén, Viktória Varga, Fatime Szalai, Risa Miyaura, Nóra Förhécz, Bálint Csikós, Rebeka Gelencsér, Zsófia Gábriel, Timea Komlódi, Katalin Dezső, Ildikó Krencz, Dorottya Moldvai   +11 more
wiley   +1 more source

The IP₃R inhibitor desmethylxestospongin B reduces tumor cell migration, invasion and metastasis by impairing lysosome acidification and β1-integrin recycling. [PDF]

Biochim Biophys Acta Mol Basis Dis
Bustos G, Ahumada-Castro U, Silva-Pavez E, Huerta H, Puebla A, Quezada C, Morgado-Cáceres P, Casanova-Canelo C, Smith-Cortinez N, Podunavac M, Oyarce C, Lladser A, Farias P, Lovy A, Molgó J, Torres VA, Zakarian A, Cárdenas JC.   +17 more
europepmc   +1 more source

Ethylenediaminetetraacetic Acid and Other Dentine Bioactive Molecule‐Releasing Agents for Regenerative Endodontic Procedures: A Systematic Review

International Endodontic Journal, EarlyView.
ABSTRACT Background The bioactive molecules released from dentine are key to stem‐cell recruitment, proliferation and differentiation in regenerative endodontics. However, there is limited and conflicting information regarding current and potential agents for releasing dentine bioactive molecules for regenerative endodontic procedures.
Arwa Al‐Maswary, Xiaoxuan Deng, Haizal M. Hussaini, Lara T. Friedlander, Paul R. Cooper   +4 more
wiley   +1 more source

Mast cell β1 integrin localizes mast cells in close proximity to blood vessels and enhances their rapid responsiveness to intravenous antigen. [PDF]

J Allergy Clin Immunol
Galli SJ.
europepmc   +1 more source

Risk Factors and Management of Gingival Enlargement: A Systematic Review and Meta‐Analysis

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Objective To identify risk factors/indicators of gingival enlargement (GE) and to summarise evidence for its management. Methods A systematic review was undertaken following PRISMA guidelines and divided into PECOTS and PICOTS questions, related to risk factors/indicators and treatment studies, respectively.
Luigi Nibali, Emily Ming‐Chieh Lu, Helvis E. S. Paz, Jing Kang, Nagihan Bostanci, Georgios N. Belibasakis   +5 more
wiley   +1 more source